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Tag: Bone

Young rat
A new study published in the journal Aging has examined the effects of vibration on cellular senescence and osteoporosis. Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead, they emit potentially harmful chemical signals, collectively...
The Sheekey Science Show
As we reported yesterday on Lifespan.io, the common supplement alpha-ketoglutarate has been shown in a rodent study to combat osteoporosis, the age-related loss of bone tissue caused by an imbalance between bone-building and bone-destroying cells. Today, we present a related video from the Sheekey Science Show, a popular science show that often discusses aging and...
Osteoporosis Hip
Research on rodents shows that alpha-ketoglutarate could be an effective way to treat or even prevent osteoporosis [1]. BoneBone tissue serves as the primary structural component of our bodies. It protects our delicate inner organs, plays a key role in whole body calcium, phosphorus, and acid-base homeostasis, and allows movement to occur by giving our...
CGI image of the gut and microbiome
Researchers from the University of Geneva have shown that a warm environment improves bone strength and highlights a related link with gut microbiome composition. These findings also pave the way for novel therapies for the treatment of osteoporosis. Turning up the heat Osteoporosis is an age-related bone disease typified by the loss of bone density,...
X-ray hand
Because of bone's natural self-healing abilities, it has provided regenerative medicine with some of its earliest successes. However, as with many tissues, the defects that can be treated are currently limited in size.
A recent open-access mouse study published by Xi'an Institute of Tissue Engineering and Regenerative Medicine scientists in the journal Bone Research describes how the ALPL gene affects bone aging and suggests that metformin might constitute a viable therapeutic option to prevent it [1]. Study abstract Mutations in the liver/bone/kidney alkaline phosphatase (Alpl) gene cause hypophosphatasia...