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Tag: Bone

Hand arthritis
In a paper published in Nature Aging, a group of scientists outlines a previously unknown pathway that leads to osteoarthritis and describes a promising treatment [1]. Less than a killer, more than a nuisance There are plenty of deadly age-related diseases, and then there are others that shorten our healthspan rather than lifespan, making the...
Rat bones
A new study in ACS Applied Materials and Interfaces used a combined geroscience and tissue engineering approach to regenerate bone in aged rats [1]. Replacement or rejuvenation? Too often, tissue engineering and longevity therapeutics are viewed as competing strategies – two different paths to potentially combat aging. In tissue engineering, cells and biomaterials are used...
Hand arthritis
A study published in Aging has found that osteopontin's effects on bone remodeling may be at least partially responsible for osteoarthritis. BoneBone tissue serves as the primary structural component of our bodies. It protects our delicate inner organs, plays a key role in whole body calcium, phosphorus, and acid-base homeostasis, and allows movement to occur...
Bone structure fails as we age but can be rejuvenated
Researchers have shown that age-related loss of bone maintenance is caused by changes in gene expression [1]. Perhaps most importantly, those changes can also be reversed and the bone marrow stem cells rejuvenated. Bones become weaker as we age as stem cell function declines With advancing age, it is typical for our bones to become...
Young rat
A new study published in the journal Aging has examined the effects of vibration on cellular senescence and osteoporosis. Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead, they emit potentially harmful chemical signals, collectively...
Osteoporosis Hip
Research on rodents shows that alpha-ketoglutarate could be an effective way to treat or even prevent osteoporosis [1]. BoneBone tissue serves as the primary structural component of our bodies. It protects our delicate inner organs, plays a key role in whole body calcium, phosphorus, and acid-base homeostasis, and allows movement to occur by giving our...