It’s funny that people often talk about aging without a real understanding of what aging is. They talk about the aches and pains that come with getting older and yet remain oblivious to the actual processes that are driving aging.
Aging is a series of processes that include direct damage, accumulation of cellular waste, errors, and imperfect repairs as well as the responses to them. These processes result in the familiar signs of aging and ultimately to the development of age-related diseases that eventually kill us.
There are multiple aging theories, but one of the most popular and well supported is the Hallmarks of Aging, a 2013 paper that defined aging as nine distinct categories (hallmarks) and explained how these processes interact with each other. This diagram shows the primary processes along with the cascading secondary and tertiary processes that result in aging or click on the hallmarks below.
You can learn more about each of the hallmarks of aging by clicking on the hallmark you are interested in using the slider below.
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Understanding these processes gives us insights into how we might directly intervene against them in order to prevent age-related diseases. Researchers are working on solutions to each of these hallmarks right now, and you can see how progress is going by checking out the Rejuvenation Roadmap.
Steve serves on the LEAF Board of Directors and is the Editor in Chief, coordinating the daily news articles and social media content of the organization. He is an active journalist in the aging research and biotechnology field and has to date written over 600 articles on the topic, interviewed over 100 of the leading researchers in the field, hosted livestream events focused on aging, as well as attending various medical industry conferences. His work has been featured in H+ magazine, Psychology Today, Singularity Weblog, Standpoint Magazine, Swiss Monthly, Keep me Prime, and New Economy Magazine. Steve is one of three recipients of the 2020 H+ Innovator Award and shares this honour with Mirko Ranieri – Google AR and Dinorah Delfin – Immortalists Magazine. The H+ Innovator Award looks into our community and acknowledges ideas and projects that encourage social change, achieve scientific accomplishments, technological advances, philosophical and intellectual visions, author unique narratives, build fascinating artistic ventures, and develop products that bridge gaps and help us to achieve transhumanist goals. Steve has a background in project management and administration which has helped him to build a united team for effective fundraising and content creation, while his additional knowledge of biology and statistical data analysis allows him to carefully assess and coordinate the scientific groups involved in the project.
2 Comments
Dr Teresa Kinyari Mwendwa
September 9, 2020
Could I use this image for a policy presentation?
Steve Hill
September 9, 2020
Hi, yes you can use our infographic as long as you credit the source.
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