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August 11, 2020
On this week's Lifespan News, Brent Nally discusses a DNA methylation clock that determines our skin age, fruit flies and caloric restriction, the senescence resistance of aging mole rats, a mitochondrial protein that regulates health and longevity, the "love hormone" oxytocin as a therapy for Alzheimer's disease, and other rejuvenation topics.
August 11, 2020
Researchers have found that CLOCK, a protein that regulates the circadian cycle of our cells, also fights cellular senescence by promoting chromatin stability [1]. Since its very beginning, life on Earth had to adapt to our planet's natural 24-hour rotation cycle. Rising to the challenge, nature invented biological mechanisms called circadian clocks (from the Greek...
August 10, 2020
Epigenetic alterations, which are one of the proposed reasons we age, are the changes to gene expression that our cells experience as we get older. These alterations harm the fundamental functions of our cells and can increase the risk of cancer and other age-related diseases. Depending on your view, epigenetic alterations are either the result...
August 07, 2020
Senescent cells accumulate in our bodies as we age, increasing inflammation and raising our risk of suffering from cancer and other age-related diseases. A new biotech startup plans to reset aged senescent cells to a youthful state to deal with this problem. The rejuvenation biotechnology field is growing at a steady pace these days, with...
August 06, 2020
A new study published in Cell Stem Cell has shown how astrocytes, glial cells that perform multiple critical functions in the brain, can become neural stem cells (NSCs) in response to injury. Astrocytes' normal functions The term 'astrocyte', meaning star-shaped cell, refers to a very heterogenous population of cells that perform maintenance, management and constructive...
August 05, 2020
Researchers have taken a look at how caloric restriction seems to improve intestinal stem cell function in a new open-access study. Inflammaging is a precursor of age-related diseases The lining of the intestines helps to prevent the entry of microbes and unwanted molecules into the bloodstream beyond; however, as we age, the integrity of this...