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April 08, 2020
Intermittent fasting is a common topic in the longevity community, and a new study suggests that there could be some benefits from adopting this lifestyle. A new study published in the Journal of Proteomics builds on previous studies and suggests that intermittent fasting has a host of benefits in humans, not just mice. This study...
April 07, 2020
Could therapies designed to remove senescent cells, which accumulate with age, potentially be used to treat asthma? The researchers of a recent review certainly believe this could be the case, and there is plenty of reason to think they could be right. Senescent cells and aging As we grow older, increasing amounts of our cells...
April 06, 2020
New research shows that resveratrol, a chemical found in red wine, contributes to genomic stability by reducing the occurrence of DNA double-strand breaks and prolongs lifespan in genetically modified mice that are prone to carcinogenic mutations [1]. DSBs and genomic instability Genomic instability, one of the hallmarks of aging, is a condition characterized by frequent...
April 03, 2020
A new study suggests that the enzyme intestinal alkaline phosphatase (IAP) appears to help to prevent age-related loss of intestinal barrier integrity in mice, fruit flies, and potentially humans. Improving intestinal barrier integrity There can now be little doubt that the decline of intestinal barrier integrity and the resulting inflammation play an important role in...
April 02, 2020
A new study published in Aging shows a clear link between the natural response to genomic damage and cellular senescence, illustrating a principal method by which the effects of a primary hallmark of aging flow downstream. An ATM you don't want to withdraw from When our DNA is damaged, the cell responds with signals, summoning...
April 01, 2020
Today might be April Fool's Day, but COVID-19 is no joke, aging isn't either, and the combination of the two definitely isn't - and the people attempting to reverse the hallmarks of aging in order to give us longer, healthier lives aren't messing around. Here's what's happened in the world of rejuvenation in March. LEAF...