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October 28, 2020
New research published in Stem Cell Research and Therapy has improved the regenerative potential of chondrocytes in vitro. CartilageCartilage tissue is found in various places throughout the human body, including the ears, the nose, between the ribs, and the trachea. While trauma can compromise cartilage in each of these locations, most cartilage problems occur at...
October 27, 2020
On Lifespan News this week, Brent Nally discusses skin regeneration, senolytics in human trials, T cell progenitors that boost the effectiveness of stem cell therapies, antibodies for glucosepane, and big pharma attempting to discover more senolytic drugs. Further Reading Regenerating Skin With a Single Protein A New Senolytic Enters Human Trials T Cell Progenitors Boost...
October 27, 2020
Aging research is still an emerging field, and its emergence has been laden with difficulties. Until recently, the budgets were scarce, the ideas ridiculed, and public involvement nonexistent. The tide is turning, with more private and institutional players eager to spend money and effort on the noble goal of extending human lifespan and healthspan. Still,...
October 26, 2020
Today, we want to highlight another study that takes us a step closer to getting partial cellular reprogramming to the clinic. Partial Cellular ReprogrammingDrs. Takahashi and Yamanaka showed that they could use Oct4, Sox2, Klf4, and c-Myc (OSKM) to reprogram cells back to pluripotent, embryonic stem cells. While this discovery showed that cellular identity and aging could...
October 23, 2020
In this panel discussion from Ending Age-Related Diseases 2020, Vadim Gladyshev of Harvard Medical School chairs a panel with Steve Horvath of UCLA, Kristen Fortney of BioAge Labs, Stanislav Skakun of Biodata, and Peter Fedichev of GERO to discuss biomarkers and their critical role in developing and evaluating drugs and therapies that treat the root...
October 22, 2020
A new analysis has revealed a core set of genes involved in aging in both humans and mice. Together with a broader set of age-related genes assembled by the study [1], this resource will serve as a launching point for further investigations of the mechanisms behind aging and age-related diseases. The heart of the matter...