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LSN Longevity Prize
The Longevity Prize is a series of prizes designed to honor the researchers who are helping to build a future in which age-related diseases are a thing of the past. This new initiative aims to accelerate progress in the rejuvenation biotechnology field and encourage innovation. While great strides in our understanding of aging have been...
Blood vessels brain
Researchers publishing in Aging have found that enlarged perivascular spaces (ePVS) in the brain are correlated with vascular disorders [1]. These spaces, which are part of the brain's glymphatic system, allow for the drainage of potentially dangerous metabolites such as beta amyloid [2]. A known biomarker of brain disorders As they become enlarged, perivascular spaces...
Skin aging
In a new systematic review published in Scientific Reports, multiple genes driving skin aging were identified [1]. The authors start by explaining the intrinsic (genetic and chronological) and extrinsic (environmental) factors that drive skin aging. While the environmental factors that affect the rate of skin aging, such as sun exposure and smoking, can be controlled,...
Researchers have been able to achieve substantial recovery of cellular and organismal activity in pigs that had been dead for a full hour [1]. When is it too late? Advances in resuscitation have already moved the boundaries of life and death, making it possible to revive a person several minutes after the heart stops beating....
Lewy bodies
A team of researchers publishing in Nature Communications has described nanobodies that can destroy the α-synuclein aggregates that characterize Lewy bodies, which are associated with dementia and Parkinson's disease [1]. What are nanobodies? Traditional antibody therapies, while promising in some studies, are too large to enter cells in order to affect the aggregates there [2]....
Steve Horvath
Dr. Steve Horvath hardly needs an introduction, so we will be brief: he is the inventor of the epigenetic clock and, currently, principal investigator at Altos Labs. We talked about the recent developments in this immensely important field, including pan-mammalian clocks, two-species clocks, and single-cell clocks, along with the challenges the field faces. You are...