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Joao Pedro de Magalhaes
Professor João Pedro de Magalhães leads the Genomics of Ageing and Rejuvenation Lab at the Institute of Inflammation and Ageing in the University of Birmingham. He is also CSO of YouthBio Therapeutics, a US-based biotech company that develops rejuvenation gene therapies based on partial reprogramming by Yamanaka factors. Last year, he co-authored The hoverfly and...
Gene pill
In a study printed in PNAS, researchers have shown that telomerase reverse transcriptase (TERT) can be given to cells in living mice through a viral vector, taking the idea of life-extending gene therapies from science fiction to reality. Why a cytomegalovirus? The human cytomegalovirus (CMV) is widely known as an endemic virus that, while usually...
Senior man walking
Publishing in Nature Communications, Dr. Tom Yate, Dr. Neliesh J. Samani, and colleagues used data from approximately 400,000 people in the UK Biobank in order to examine the relationship between walking pace and telomere length. Why We Age: Telomere AttritionTelomeres are DNA regions located at the ends of a chromosome. Their normal length is 8-10...
LSN Plastic Nanoparticles
Hosted by Ryan O'Shea, this episode of Lifespan News is on how plastic nanoparticles might lead to at least one hallmark of aging being accelerated. Script Studies show that everyday objects such as baby bottles and tea bags can release plastic particles into the environment and into our bodies. Now, new research shows the scale...
EARD2022 Banner
This year sees us hosting the fifth Ending Age-Related Diseases conference, and once again we are bringing you four action-packed days of aging research, rejuvenation biotechnology, and biotech investment. A virtual event focused on healthy longevity Join us on August 11-14 for what is sure to be an unmissable event for people interested in longer...
Drug combination
Scientists have shown that a combination of rapamycin, acarbose, and phenylbutyrate has a synergetic rejuvenation effect when administered to 20-month-old mice for three months [1]. Fighting on multiple fronts In this paper, the authors argue that to tackle such a multifaced process as aging, it might be beneficial to target different molecular pathways using several...