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Vitalik at Zuzalu
Vitalik Buterin holding Zuzu, the puppy rescued by people of Zuzalu. Photo: Michelle Iai Don’t try finding Zuzalu on a map; it doesn’t exist anymore. It was a β€œpop-up city” conceived by the tech entrepreneur Vitalik Buterin, creator of Ethereum, and a group of like-minded people to facilitate co-living and collaboration in fields like crypto,...
Bacteriophages
Researchers publishing in Nature Microbiology have determined that the viruses populating the intestines of centenarians are slightly different from those of the merely old. Viruses for bacteria, not people We have written previously about a study showing that centenarians have youthful bacterial gut compositions (enterotypes) similar to those of younger people. This study looks more...
Mountaintop
Scientists have found that continuous oxygen restriction drastically extends the lifespan of progeroid mice, but the effect's mechanism remains a mystery [1]. Can less oxygen be better? Hypoxia is a condition in which an organism or an organ in the body does not receive enough oxygen. However, how much is enough, and whether we are...
Adrenal glands
A paper published today in Nature Aging has explained a relationship between cellular senescence, cancer of the adrenal glands, and sex differences. A closer look at age-related cancer Over 90% of cancer diagnoses are made in people over a half century old [1]. This is not just because of genomic instability leading to cancerous mutations;...
Needles in haystack
In a recent paper published in International Journal of Medical Sciences, researchers have described how they used artificial intelligence and machine learning tools to find mTOR-inhibiting molecules [1]. mTOR is a common target for lifespan extension interventions The mechanistic target of rapamycin (mTOR) is a well-known molecule in the rejuvenation world. Previous studies have demonstrated...
SENS Mitomouse 2
Financed by Lifespan.io's crowdfunding efforts, SENS Research Foundation has engaged in fruitful research into ways of dealing with mitochondrial dysfunction, the gradual loss of function of our cells' power plants. Here, the organization reports its successes in handling this aspect of aging. The cellular machinery and higher-level structures of our bodies inevitably damage themselves as...