Month: August 2021

In his introductory speech for our fourth annual Ending Age-Related Diseases conference, Lifespan.io president Keith Comito discusses the epic of Gilgamesh and how it relates to our modern quest of curing the diseases of aging. Script Good morning, and welcome to the fouth annual Ending Age-Related Diseases conference, and I hope you all are healthy...

A team of Chinese researchers has outlined the cellular link between age-related inflammation (inflammaging) and the physical aging of heart muscle cells (cardiomyocytes). NLRP3 and why it matters We have previously discussed the NLRP3 inflammasome, which releases inflammatory cytokines upon exposure to irritants [1], including reactive oxygen species (ROS) [2]. The researchers hypothesized that ROS,...

On this culinary episode of Lifespan News, we discuss a new study showing how much lifespan certain foods add or subtract. Script It’s been all over the news and all over the internet - eating a hot dog will take 36 minutes off your life. But what does the study actually say, and what does...

A study published in Cell Reports has shown that early-life exposure to antibiotics that destroy the gut flora can harm the lifelong development of mice, including lifespan. Three groups with different microbiota To begin the study, the researchers fed 20 baby mice, as well as their mothers, amoxicillin and neomycin, and they established a control...

Today, we chronicle the progress of partial cellular reprogramming and discuss how this powerful treatment may be able to reprogram cells back into a youthful state, at least partially reversing epigenetic alterations, one of the proposed reasons we age. We have created an introduction video about cellular reprogramming and if you would like to learn...

With so many health and disease outcomes connected to the biological aging processes, research into quantifying and tracking aging has surged in recent years due to the work of Steve Horvath, Morgan Levine, and others. Currently, epigenetic analysis of biological aging is thought to be the most comprehensive and accurate measurement of aging that is...