Help us: Donate
Follow us on:
×

Menu

Back

Tag: Vascular Aging

Plastic for Dinner
Scientists have found that exposure to plastic nanoparticles drives cellular senescence and dysfunction in endothelial cells taken from a pig's coronary artery [1]. A widespread pollutant Plastic has changed the face of civilization, but the convenience of plastic comes at a price – mostly in terms of environmental pollution from plastic manufacturing and waste. There...
Brain Blood Vessels
After sifting through 1,600 FDA-approved drugs, scientists have shown that Viagra is significantly correlated with lower Alzheimer’s disease risk [1]. Re-repurposing Viagra? Viagra (sildenafil) is one of the most recognizable drugs in the world. Yet, sildenafil's hailed effect on erectile dysfunction was discovered serendipitously. Originally, sildenafil was studied as a candidate drug for heart-related chest...
Blood cells in an artery
A mouse study published in Aging Cell has outlined the similarities between artificially restricted cerebral blood flow and the reduced blood flow associated with aging. Aiming to understand vascular dementia Prior research has shown that reduced cerebral blood flow, known as hypoperfusion, results in vascular dementia and brain atrophy through multiple mechanisms, including neuroinflammation and...
Elastrin logo
Rejuvenation biotechnology startup founder Kizoo has provided Elastrin, a company that focuses on removing calcification from tissue, with seed funding. The company Elastrin is named for elastin, which comprises the fibers affected by this calcification. The company is using a proprietary antibody to deliver a nanoparticle-encased therapeutic agent directly to the fibers in question. The...
Blood vessels
Tissue engineering company Humacyte is about to make a special purpose acquisition company (SPAC) deal in order to go public. The company is developing bioengineered Human Acellular Vessels (HAVs), which provide prosthetic vasculature to support the repair, reconstruction, and replacement of blood vessels damaged by injury or disease. What is a SPAC? A special purpose...
Cerebral blood vessels
A new study conducted by researchers from Germany and the UK has shown that accumulation of medin, an amyloid of the protein MFG-E8, leads to cerebrovascular (brain blood vessel) disease in wild-type mice [1]. Why we Age: Loss of ProteostasisThe loss of proteostasis is the failure of the protein building machinery of the cell and...