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Tag: Vascular Aging

Blood cells in an artery
June 16, 2021
A mouse study published in Aging Cell has outlined the similarities between artificially restricted cerebral blood flow and the reduced blood flow associated with aging. Aiming to understand vascular dementia Prior research has shown that reduced cerebral blood flow, known as hypoperfusion, results in vascular dementia and brain atrophy through multiple mechanisms, including neuroinflammation and...
Elastrin logo
March 04, 2021
Rejuvenation biotechnology startup founder Kizoo has provided Elastrin, a company that focuses on removing calcification from tissue, with seed funding. The company Elastrin is named for elastin, which comprises the fibers affected by this calcification. The company is using a proprietary antibody to deliver a nanoparticle-encased therapeutic agent directly to the fibers in question. The...
Blood vessels
February 22, 2021
Tissue engineering company Humacyte is about to make a special purpose acquisition company (SPAC) deal in order to go public. The company is developing bioengineered Human Acellular Vessels (HAVs), which provide prosthetic vasculature to support the repair, reconstruction, and replacement of blood vessels damaged by injury or disease. What is a SPAC? A special purpose...
Cerebral blood vessels
October 02, 2020
A new study conducted by researchers from Germany and the UK has shown that accumulation of medin, an amyloid of the protein MFG-E8, leads to cerebrovascular (brain blood vessel) disease in wild-type mice [1]. Why we Age: Loss of ProteostasisThe loss of proteostasis is the failure of the protein building machinery of the cell and...
Red meat
July 10, 2020
Researchers suggest that trimethylamine, a metabolic byproduct that is created when bacteria in the gut break down foods such as red meat, may be a key player in vascular aging. Trimethylamine and vascular aging Some researchers believe that trimethylamine damages our arteries, according to a new study conducted by researchers at the University of Colorado...