Help us: Donate
Follow us on:
×

Tag: Hallmarks of Aging

Needle in a haystack
Researchers publishing in Nature Communications have determined that interventions that extend lifespan in mice may not have significant effects on the processes of aging. Improvement is not the same as slowing decline The researchers begin this paper by noting that previous studies have outlined a broad variety of dietary, environmental, and genetic factors that are...
New Hallmarks
Publishing in Aging five months after their panel discussion in Copenhagen, many well-known researchers have explained their reasons for wishing to add new hallmarks of aging to the existing paradigm. A new addition to an old paradigm What is Aging? The Nine Reasons We AgeAging is a series of processes that include direct damage, accumulation...
Antique clock
Scientists have shown that only some of the hallmarks of aging affect methylation clocks that are used to measure biological age [1]. The big black box Epigenetic clocks that measure biological age based on aging-related changes in genome methylation have been a great success. They enable researchers to analyze the effects of various interventions on...
Joao Pedro de Magalhaes
Professor João Pedro de Magalhães leads the Genomics of Ageing and Rejuvenation Lab at the Institute of Inflammation and Ageing in the University of Birmingham. He is also CSO of YouthBio Therapeutics, a US-based biotech company that develops rejuvenation gene therapies based on partial reprogramming by Yamanaka factors. Last year, he co-authored The hoverfly and...
Evolution
In a paper in Frontiers in Genetics, Maël Lemoine of France’s CNRS offers an evolutionary perspective on the hallmarks of aging [1]. This review examines the appearance of the hallmarks in different groups across the tree of life, with the aim of providing a comprehensive picture of how the mechanisms of aging have evolved. With...
Steve Horvath at EARD2021
In his talk at Ending Age-Related Diseases 2021, Steve Horvath discussed a cytosine-based, pan-mammalian epigenetic clock that works across a wide variety of species. He also discussed how several of the hallmarks of aging do not seem to have any effect on epigenetic alterations.  Script Hello, thank you for your interest. My name is...

Want the latest longevity news? Subscribe to our Newsletter!