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Tag: Cytokines

mRNA
The current pandemic has brought mRNA vaccines into the spotlight and have likely sped up the widespread adoption and usage of this technology. Now, a company has its sights set on treating cancer with mRNA technology, and the initial animal data is positive. mRNA steps up to treat cancer mRNA vaccines look like they are...
Gut brain inflammation
A recent review published in Cureus shows why fecal microbial transplantation (FMT) might be able to help sufferers of Alzheimer's disease, showing how tightly the gut and brain are intertwined. Why would this ever work? The gut and brain are closely linked through biochemistry, and last month, we published an article about how the gut...
Heart Inflammation
A team of Chinese researchers has outlined the cellular link between age-related inflammation (inflammaging) and the physical aging of heart muscle cells (cardiomyocytes). NLRP3 and why it matters We have previously discussed the NLRP3 inflammasome, which releases inflammatory cytokines upon exposure to irritants [1], including reactive oxygen species (ROS) [2]. The researchers hypothesized that ROS,...
A novel treatment that inhibits the activity of the Cdc42 protein has been found to extend the lifespan of aged mice, most likely through epigenetic changes and regulation of inflammatory cytokines. Cdc42 is linked with lifespan Cdc42 is a RhoGTPase, a kind of signaling protein involved in a variety of processes in eukaryotic cells. It...