March 19, 2024
Ora Biomedical has created a robot for high-throughput screening of life-extending compounds in worms, and you can buy an experiment for 100 dollars. Things in the longevity field look bright or gloomy, depending on who you ask. It is true that we now understand much more about aging than we did just a few years...
December 11, 2023
The Journal Club is back for one final time this year! Dr. Oliver Medvedik will return on December 15th at 12:00 Eastern on the Lifespan.io Facebook page to review the recent paper "A drug-like molecule engages nuclear hormone receptor DAF-12/FXR to regulate mitophagy and extend lifespan". Join us and find out how researchers are boosting...
January 18, 2023
In a new review paper published in GeroScience, the researchers explored the translatability of anti-aging interventions across species and received somewhat alarming results [1]. Necessary, but not the best Model organisms have been widely and successfully used to understand the molecular processes driving disease pathologies, identify drug candidates, and test therapeutic interventions. Modern drug development...
June 29, 2022
In a new study published in GeroScience, researchers have shown that it is possible to significantly increase yeast lifespan by overexpressing genes highly conserved across various species [1]. Survival and aging The question of the effects of nature versus nurture, or programmed versus stochastic, sparks hot scientific debate in other fields as well as aging....
May 19, 2022
A study published in Redox Biology has reported that the upregulation of thioredoxin, a fundamental part of mitochondrial defense against reactive oxygen species, is associated with longevity in mutant C. elegans worms. Free radicals, revisited Why we Age: Mitochondrial DysfunctionAs they age, the mitochondria in our cells lose their ability to provide cellular energy and...
May 06, 2022
Scientists have shown that an active ingredient of cannabis significantly upregulates autophagy, extending both lifespan and healthspan in C. elegans nematode worms. Two of the most well-known components of marijuana are tetrahydrocannabinol (THC) and cannabidiol (CBD). They have the same atomic composition, but differ in structure and in some of their qualities. THC is what...