Tag: Amyloid Beta

In the Journal of Inflammation, researchers from Johns Hopkins University have published a detailed review of the relationship between brain inflammation and the principal diseases of dementia. A focus on genetics and environment One out of twenty Americans over 85 have Parkinson's disease [1], and seven out of twenty have Alzheimer's [2]. While genes are...

Scientists have synthesized a molecule that alleviates Alzheimer's in a mouse model by targeting inflammation [1]. Aβ or inflammation? Two of the most prominent - and probably interconnected - symptoms of Alzheimer's disease are the accumulation of amyloid beta (Aβ) and chronic neuroinflammation. While the first one has been garnering most of the attention, innumerable...

Researchers publishing in Aging Cell have found that administering Vitamin D to Alzheimer's patients may actually make the problem worse. A matter of cause and effect Vitamin D deficiency is strongly linked to Alzheimer's disease [1], and previous research has suggested that addressing this deficiency might be useful in treating the disease [2]. These researchers,...

In a new study published in Pharmacology Biochemistry and Behavior, researchers have shown that a combination of two compounds targeting different autophagy pathways is effective in fighting the pathological mechanism of Alzheimer's disease in a mouse model [1]. Cleaning up is a big deal The accumulation of "junk", such as misfolded proteins and damaged organelles,...

A team of researchers publishing in the Nature publication Molecular Psychiatry has described how a newly discovered interaction of amyloid beta (Aβ) is being used in the development of a vaccine for Alzheimer's disease. A specific antibody for truncated Aβ The biochemistry of Alzheimer's is extremely complicated. Aβ is not always one molecule with a...

New results from the AMBAR trial show that plasma exchange leads to statistically significant functional and cognitive improvements in patients with mild to moderate Alzheimer's [1]. As our readers surely know, the world is spending much more resources on fighting the diseases of aging than on solving aging itself. In particular, tens of billions of...