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Tag: Amyloid Beta

Amyloid tangles
A team of researchers publishing in the Nature publication Molecular Psychiatry has described how a newly discovered interaction of amyloid beta (Aβ) is being used in the development of a vaccine for Alzheimer's disease. A specific antibody for truncated Aβ The biochemistry of Alzheimer's is extremely complicated. Aβ is not always one molecule with a...
Alzheimer's
New results from the AMBAR trial show that plasma exchange leads to statistically significant functional and cognitive improvements in patients with mild to moderate Alzheimer's [1]. As our readers surely know, the world is spending much more resources on fighting the diseases of aging than on solving aging itself. In particular, tens of billions of...
Blueberries
A group of researchers has confirmed the neuroprotective effect of blueberry extract and identified a possible mechanism of action that might facilitate drug development [1]. The delicious cure? Blueberries have long been on the list of "superfoods" that supposedly protect our health and maybe help us live a bit longer. Flavonoids, a class of plant-derived...
Balanced stones
Scientists have demonstrated that “the Alzheimer’s allele” APOE e4 helps cognition earlier in life prior to the onset of the disease [1]. This might point at a possible reason for some aspects of aging. What makes us stronger kills us later The risk of developing Alzheimer's, one of the deadliest age-related diseases, is considerably elevated...
Journal Club
Journal Club returns on July 27th at noon Eastern / 17:00 UK live on our Facebook page. A new way to look at Alzheimer's The topic for this month will be a new study that challenges the amyloid hypothesis of Alzheimer's disease with new human data. The data suggests that the cognitive impairment that accompanies...
Solving brain puzzle
A recent study, led by the University of Cincinnati in collaboration with the Karolinska Institute in Sweden, challenges the popular amyloid hypothesis that has dominated Alzheimer’s research for decades. Amyloid accumulation may be the consequence, not the cause Over 100 years ago, Alois Alzheimer originally identified amyloid-beta plaques in the brains of people with the...