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Month: March 2021

Scientists have alleviated symptoms of the rare premature aging disease ataxia-telangiectasia using NAD+ supplementation in a mouse model [1]. This success deepens our understanding of the role NAD+ plays in aging. The ubiquitous facilitator The coenzyme nicotinamide adenine dinucleotide (NAD+) is one of the foundations of life as we know it, and it may have...
Researchers have grown mini thyroids.
This week on Lifespan News, Brent Nally discusses thyroid organoids for potential human use, a human trial showing that clearing amyloid plaques slows mental decline, reduced NMN as a NAD+ precursor, shortened telomeres and kidney fibrosis, and our STSTW episode on meditation. Further Reading Thyroid Organoids Created From Human Tissue Human Trial Suggests Clearing Plaques...
Does death give life meaning? No, not really.
In this episode of X10, we discuss what gives life meaning and exactly what role that the ending of life plays in that meaning. Check out the Dog Aging Project, which is run by cool people trying to give our pets longer, healthy lives: http://www.dogagingproject.org Script Do any of these quotes sound familiar to you?...
An image of colorectal cancer.
In a cell culture study, researchers have discovered that forcing cancer cells to differentiate into somatic cells can cause them to stop proliferating. Cancer, stem cells, and proliferation The danger of cancer is from its proliferation: its uncontrolled division within the body. This proliferation is explained by the mutated cells exhibiting stem-like properties; in other...
Dictator
Suppose there was a country ruled by an evil dictator. Further, suppose the entire world was plagued by a terrible disease affecting 100% of the population. The disease isn’t infectious, but it is congenital. It progresses extremely slowly over the course of several decades, but it eventually ends up severely impairing one’s quality of life,...
NMN is short for nicotinamide mononucleotide, a naturally occurring molecule present in all species. On the molecular level, it is a ribonucleotide, a basic structural unit of nucleic acid RNA.
What is NMN? NMN is short for nicotinamide mononucleotide, a naturally occurring molecule present in all species. On the molecular level, it is a ribonucleotide, a basic structural unit of nucleic acid RNA. In form it consists of a nicotinamide group, a ribose and a phosphate group. It is a precursor molecule of the essential...

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