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Month: April 2020

Researcher using a microscope
Today, we want to highlight a new review that takes a look at senescent cell removal therapies and their potential to treat and reverse age-related diseases by reversing one of the aging processes. The current approach of medicine to treating age-related disease is broken The current approach to treating age-related diseases is predominately to treat...
On Thursday, May 7th at noon EDT, on our Facebook page, Lifespan.io will be livestreaming an online roundtable discussion with key leaders of our field to discuss the current pandemic, its relationship to aging research, and how the current situation might impact the future of healthcare. Join David Sinclair, Aubrey de Grey, former director of...
Aubrey de Grey on COVID-19
Dr. Aubrey de Grey is a biomedical gerontologist and the founder of the concept of strategies for engineered negligible (SENS), a strategy which breaks down the aging process into seven categories with proposed solutions to each. He is the Chief Science officer at the SENS Research Foundation, a non-profit dedicated to combating the aging process....
Mouse with prominent whiskers
A group of researchers has demonstrated that treatment with NMN, a precursor of NAD+, restores neurovascular coupling (NVC) in aged mice [1]. Since NVC deficiency seems to be a major factor in the age-related decline of cognitive and motor functions, this discovery presents exciting new possibilities for longevity research. Neurovascular coupling While the human brain...
Telomere shortening
Researchers have demonstrated that it is possible to restore telomerase activity in stem cells affected by telomere biology diseases, which prevent them from producing telomerase and repairing their telomeres. Telomeres and telomerase Each chromosome that stores our genetic information has a protective cap at each end known as a telomere, a specific DNA sequence that...
Blood Vessel
Researchers have developed a way to modify an existing cancer drug with toxic side effects into something that is less toxic to blood platelets and more effective at removing harmful and inflammatory senescent cells, one of the reasons we age, from mice. What are senescent cells? As you age, increasing numbers of your cells enter...