Month: April 2019

Researchers have tested nicotinamide mononucleotide on aged mice to see if it can help reverse age-related cognitive decline by improving blood flow in the brain. The brain is a hungry organ Healthy brain function relies on efficient cerebral blood flow (CBF) to wash away harmful waste products for disposal and supply the brain with an...

Scientists from Johns Hopkins Medicine have reported the successful creation of a special type of gel that mimics the lymph nodes in our bodies. This gel recruits and multiplies T cells just like actual lymph nodes do, so it could help in the fight against cancer and immune system disorders. The lymph nodes are the...

Professor Jerry Shay of the Shay/Wright lab is perhaps most well-known for his research on telomeres and telomerase and their relation to cancer and aging. He has been instrumental in the development of telomerase inhibitors, which turn off the expression of telomerase in cancer cells; this expression is one way in which cancer cells become...

Rapamycin is a promising anti-aging therapeutic derived from a bacterium that was first found on Easter Island (it's named for Rapa Nui, the official name of Easter Island). It inhibits mTOR (mechanistic target of rapamycin), thus inhibiting the immune system response that would, in some cases, lead to organ rejection. This is the on-label, FDA-approved...

We have known since the 19th century that young blood has surprising curative and rejuvenation abilities. It's quite strange, but it happens to be true. In recent years, scientific efforts to understand what it is about young blood that causes rejuvenation have ramped up. We now know that young and old mice with surgically connected...

A small update from the MMTP project team following meeting the lead investigator Dr. Alexandra Stolzing in Berlin recently. Hi everyone, it has been a while and as we have recently spoken to Dr. Alexandra Stolzing at the Undoing Aging conference in Berlin about the MMTP we wanted to give a small update. Dr. Stolzing...