Fauna Bio � Small molecule drug development

Fauna Bio, has an impressive repository called a Biobank, containing a vast assortment of tissue samples from hibernating animals. These samples represent over 22 different types of tissue and have been collected at 13 specific times throughout the year, which provides a rich source of data, including billions of genetic sequences.

They also perform a detailed analysis across 415 different species, including humans, to identify genes related to specific mammalian traits and find genes that have remained unchanged across these species. This could indicate that these genes have important functions.

By using machine learning algorithms, they identify clusters of these crucial genes that help prevent diseases. They also rank genes based on their potential interest for researching specific diseases. Their approach has led to a significant increase in their success rate for finding vital genes.

In a process they call “Contrast Biologies”, they compare the genes that protect animals from diseases with those causing diseases in humans. This comparison helps them pinpoint the genes most likely responsible for diseases.

One of their significant advancements is using their gene information to predict new uses for small chemical compounds, thereby aiding in drug development. They have analyzed tens of thousands of different compounds to find the ones that align best with protective genes identified in animals.

What sets them apart is their therapeutic potential. Their methods aren’t limited to just predicting new uses for these compounds. They are also able to identify the most effective genes to target for diseases currently lacking effective treatments. They do this using a variety of cutting-edge technologies, showcasing their ability to adapt and innovate in the medical field.