July 08, 2022
Vadim Gladyshev is a Professor of Medicine at Brigham and Women's Hospital and Harvard Medical School, and he is one of the most prominent figures in geroscience today. We discussed various competing hypotheses on the nature of aging, the lack of the unified theory of aging and the need for one, and several fascinating papers...
February 24, 2022
A team of researchers, including Steve Horvath, Leonid Peshkin, and Vadim Gladyshev, has published a preprint on bioRxiv showing the effects of early administration of rapamycin over the lifespans of mice. Rapamycin before and after weaning In this placebo-controlled experiment, the researchers selected the UMHET3 strain of mice, as it is a crossbreed that does...
February 03, 2022
A research paper published in Nature by Dr. Vadim Gladyshev and his team has investigated the epigenetic aging of the naked mole rat, an animal whose mortality rate does not appear to increase with age. Why we Age: Epigenetic AlterationsEpigenetic alterations are age-related changes in gene expression that harm the fundamental functions of cells and...
January 24, 2022
Vadim Gladyshev and his team have published a review in Aging Cell about the current techniques and innovations in rejuvenation biotechnology, providing an overview of how these researchers see the state of the field. The reversibility of aging The reviewers begin by discussing the connection between the perceived irreversibility of aging and the lack of...
May 10, 2021
The Journal Club hosted by Dr. Oliver Medvedik returns for another episode on May 25th at noon Eastern / 5 UK time live on our Facebook page. This month, we have one of the authors, Dr. Vadim Gladyshev, joining us, and he will be talking us through this new research. Vadim and his team report...
August 06, 2019
Today, we want to draw attention to a new study that shows how partial cellular reprogramming was able to reverse cellular aging and address age- and injury-induced blindness in mice. Epigenetic alterations One of the proposed reasons we age is the changes to gene expression that our cells experience as we get older; these are...
