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Tag: Vadim Gladyshev

DNA clock
November 29, 2019
A team of researchers, including Drs. Vadim Gladyshev and Steve Horvath, recently published a review of DNA methylation aging clocks, which use biomarkers to determine the biological age of a person. Aging causes epigenetic alterations to occur, including changes to DNA methylation, histone modification, transcriptional alterations (variance in gene expression), and remodeling of chromatin (a...
August 15, 2019
Journal Club will be returning on August 27 with your host Dr. Oliver Medvedik and special guest Alexander Tyshkovskiy, a Ph.D. student who works at the Gladyshev at Brigham and Women’s Hospital, Harvard Medical School, Boston. The topic for Journal Club this month will be the recent paper "Identification and Application of Gene Expression Signatures...
Lab mouse
August 06, 2019
Today, we want to draw attention to a new study that shows how partial cellular reprogramming was able to reverse cellular aging and address age- and injury-induced blindness in mice. Epigenetic alterations One of the proposed reasons we age is the changes to gene expression that our cells experience as we get older; these are...
EARD reception
July 30, 2019
Ending Age-Related Diseases 2019 is over, and the dust is starting to settle after what can only be described as a hugely successful event for our organization. This was our second year of running a conference, and once more, we focused on the research and investment areas of rejuvenation biotechnology. Totally sold out We wish...
DNA data
July 29, 2019
Researchers have shown that many interventions known to increase lifespan also share similar gene expression profiles, and this knowledge may help pave the way for identifying new interventions to increase healthy lifespan and delay the diseases of aging. Identifying longevity signatures A team of researchers, including Professor Vadim Gladyshev from Harvard Medical School, has just...
May 17, 2019
Earlier this year at the Undoing Aging conference in Berlin, I had the opportunity to listen to a debate between Dr. Vadim Gladyshev of Harvard Medical School and Aubrey de Grey of the SENS Research Foundation. The topic was "Is comprehensive damage repair feasible?" What followed was a friendly and interesting discussion about the three...