August 28, 2023
The Journal Club for August returns live to the Lifespan.io Facebook channel on September 5th at 12:00 Eastern hosted by Dr. Oliver Medvedik. This time we are taking a look at a paper where researchers have transfered a lifespan and healthspan boosting mechanism from the naked mole rat, a very long lived rodent, to mice....
August 24, 2023
Publishing in Nature, a team of researchers including Vadim Gladyshev, Steve Horvath, and Vera Gorbunova has investigated the role of hyaluronan, which naked mole rats have in abundance, as a protective mechanism in a mouse model. An established mechanism Naked mole rats are notably resistant to cancer, and these researchers have previously determined that this...
September 30, 2022
To understand human longevity, we need to put it into perspective. Are we relatively long-lived or short-lived creatures? After all, among all the plants and animals in nature, we find a vast variety of lifespans, from several hours to several millennia, and possibly even more. While humans are the most long-lived primates, our lifespan pales...
June 17, 2022
Naked mole rats are long-lived rodents famous for their resistance to cancer and sustained healthy lifespan. In a new study published in the Journal of Investigative Dermatology, researchers have shown that the skin of older members of this species is characterized by high expression of longevity-associated and tumor-suppressing genes [1]. Getting under the skin Skin...
May 05, 2022
A study published in Aging has shown that the skin of the naked mole rat retains nearly all of its physical and biochemical properties as these animals chronologically age, providing new insight into how and why these animals live so long. Wrinkly, but not like humans wrinkle With a wrinkly, largely hairless body, the naked...
April 15, 2022
In a study published in Nature, scientists have found an extremely strong correlation between somatic mutation rate and lifespan across several species, highlighting the importance of mutation burden for aging [1]. The question of why lifespan varies so vastly among species, including closely related ones, has always fascinated geroscientists. Studying exceptionally long-lived species might reveal...