February 12, 2024
In Nature Aging, researchers have published a method of predicting dementia over a decade before it actually occurs. Early detection was known to be possible It has been known that it is possible to observe early signs of brain deterioration years before dementia occurs [1]. However, actually performing accurate tests in a clinical setting has...
November 30, 2023
In a recent publication in PLOS One, researchers have described the metabolic effects on running in generally healthy people. A lack of activity is a known risk factor This paper begins with warnings against sedentary behavior, citing one study reporting that it is responsible for approximately 1 out of 12 early deaths in the United...
October 04, 2023
A recent study's authors investigated whether biomarkers measured earlier in life can predict if someone will live to their 100th birthday [1]. 35-year-long centenarian study Previous research has found that people who become centenarians have fewer disabilities, comorbidities, and hospitalizations earlier in life. They are also characterized by better cognitive functions than people who will...
September 21, 2023
Publishing in Aging, the Conboy research lab has outlined the problems with existing machine learning-based clocks and created a new clock based on epigenetic noise. The problem with linear regression This paper begins with a description of the elastic net, an artificial intelligence algorithm that powers the majority of biological clocks, including the Horvath biological...
September 05, 2023
The Biomarkers of Aging Consortium, an initiative uniting about 200 geroscientists around the goal to inform and guide the use of biomarkers of aging, has put out its first paper [1]. The need for biomarkers Since studies with lifespan as their endpoint can take a prohibitively long time, especially in humans, the importance of reliable...
August 17, 2023
Researchers publishing in Biogerontology have tested multiple biomarkers in an effort to use them as proxies for aging, and some of their findings were surprising. A simple study with direct measurements Unlike other association studies that are used to evaluate biomarkers of aging, this study did not use data from a pre-existing biobank or related...