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Month: February 2020

Smiley face
DNA origami, a nano-scale technique used to make very tiny smiley faces out of DNA, is becoming increasingly valuable for drug delivery and other applications, paving the way for true nanomedicine. What is DNA origami? Ever since Richard Feynman famously proclaimed in his seminal 1959 talk that "there’s plenty of room at the bottom", nanotechnology...
Interview with Lewis Gruber
At the recent Longevity Therapeutics Conference in San Francisco, we had the chance to interview Lewis Gruber of SIWA Therapeutics and discuss his company's senotherapeutic approach to cancer and senescent cells. He was accompanied by his wife, Misty, who is the CFO of SIWA. Many of our readers are familiar with CAR-T immunotherapy, which has...
Interview with Hanadie Yousef
At the recent Longevity Therapeutics Conference in San Francisco, we had the chance to interview Hanadie Yousef, the co-founder and CEO of Juvena Therapeutics. Juvena is isolating proteins from embryonic stem cells that promote tissue regrowth. Can you describe in more detail Juvena's approach to developing protein therapeutics that promote tissue regeneration in the elderly?...
Optimism
Let’s face it, getting older sucks, and not because of all the extra candles on the birthday cake. Getting cake and presents every year is great, but the loss of health and independence isn't a particularly good birthday present. (Wow, what'd I get this year? Just what I didn't want: sarcopenia and hearing loss!) Given...
Macrophage
A paper published in Nature Communications reveals that, rather than just summoning fibroblasts, inflammatory macrophages themselves form fibrous tissue that is the basis of scars. The dual role of macrophages Macrophages perform two critical roles in the immune system. After an injury, M1 macrophages spur local inflammation, causing immune cells to converge on the area...
Irina and Michael Conboy
We were at the recent Longevity Therapeutics Conference in San Francisco, and we had the opportunity to interview Irina and Michael Conboy from UC Berkeley about their pioneering work on blood factors and aging. Irina is a member of our Scientific Advisory Board, and the Conboys' work is well-known to rejuvenation advocates, as they are...