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Tag: Macrophages

Meats
A new study suggests that increased protein intake, specifically of the amino acid leucine, can exacerbate atherosclerosis by inhibiting autophagy in macrophages [1]. Protein: friend or foe? The protein we get from food is indispensable, as it allows us to produce our own proteins, but the ideal amount of dietary protein remains an open question....
Muscle factor
A paper published today in Nature Aging has shown that a macrophage-regulating factor has a significant impact on muscle regeneration. Healing slows with aging The researchers note two key reasons for the decline of regenerative abilities with aging. The first is stem cell exhaustion, the gradual depletion of stem cells and ensuing lack of functional...
The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.
The Journal Club returns on Tuesday 28th March at 12:00 PM Eastern time to the Lifespan.io Facebook channel. This month Dr. Oliver Medvedik will be exploring a recent study which looked at the effects of prolonged fasting on human macrophages and how metabolites from that fasting increased median lifespan in Caenorhabditis elegans. Abstract Periodic prolonged...
Polluted lungs
A new study published in Nature Medicine suggests that lifelong exposure to tiny airborne particles leads to their accumulation in lymph nodes in the lungs and to impaired immune function [1]. Age-related lung diseases and pollution With age, people become more susceptible to many diseases, with the lungs being one of the most affected organs....
Fat and skinny
In a new paper, Yale scientists present encouraging data from an unprecedented human study of caloric restriction, a powerful anti-aging intervention [1]. Eat less, live more Despite all the might of today’s science, simple lifestyle choices are still the clearest option for living longer and healthier. These choices include being physically active, eating better, and...
Mouse Brain Internal
Researchers, publishing in the journal Aging, have discovered that a protein called hedgehog alleviates the tissue-specific, age-related inflammation of the microglia, the maintenance cells of the brain. The aging differences between tissue types To begin this research, the team first performed a gene expression analysis on four different types of murine macrophages: bone marrow-derived macrophages...