Alkahest, a Grifols company, was founded in San Carlos, California. Steven Braithwaite is both CEO and CSO. Chronokines are proteins that increase or decrease with age. Alkahest, through proteome decoding methods is developing clinical candidates that increase or decrease the levels of key circulating chronokines to either promote innate and natural restorative biological processes or inhibit pathological degenerative processes. These therapeutics include both traditional pharmaceutical modalities as well as highly selected and refined plasma fractions and other methods for antagonizing or supplementing the most biologically active chronokines. Current clinical trials are testing our therapeutic approaches for a range of age-related medical conditions. GRF6021 is being studied in a clinical trial investigating postoperative recovery following hip and knee repair.