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Tag: T Cells

Thorough CRISPR
In a study published in Genome Biology, researchers explain how they are working to make CRISPR less prone to large, accidental deletions of genetic material [1]. A previously unknown large problem While this seems counterintuitive, previous technology only allowed for the ready identification of deletions below 100 base pairs. New technology has allowed for larger...
The Sheekey Science Show on reducing tumor growth
This time on the Sheekey Science Show, the relationship between cancer and exercise is explored. Regular physical activity is associated with a reduced risk of cancer, and an animal study has fingered the proliferation of cytotoxic CD8 T cells as the causative agents of this effect. The physical, metabolic reasons for this are explored as well, and specific exercise metabolites are identified as the causes of these cells' increased ability to infiltrate and thereby reduce tumors.
The Sheekey Science Show on Hyperbaric Oxygen Therapy
Recently on Lifespan.io, we reported the rather overhyped findings of a study that presented hyperbaric oxygen therapy as an effective way to reverse human aging. The Sheekey Science Show offers its own explanation on this study and the reactions of multiple media publications to it.
Media clown
If you have been following the mainstream media recently, you have probably seen a story about hyperbaric oxygen treatment and claims that it can reverse aging. Unfortunately, the media hype surrounding the results is nothing like the reality of the actual research paper, and this is another example of how shoddy journalism harms our field....
White blood cells
Could the immune system itself be the best way to purge senescent cells, which accumulate as we age, from the body? A new review takes a look at the role of the immune system in removing these problematic cells. What are senescent cells? As you age, increasing numbers of your cells enter into a state...
Gene editing
The successful delivery of CRISPR/Cas9 modified immune cells to cancer patients represents the first U.S. clinical trial to test the gene editing approach in humans. Researchers from the Abramson Cancer Center of the University of Pennsylvania have published data suggesting that immune cells modified using the gene editing tool CRISPR/Cas9 are able to survive and...