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Tag: SIRT1

October 08, 2020
Genes in the sirtuin family are conserved across a wide range of species and are involved in cellular metabolism, immune response, and aging. SIRT1 is known to decline during aging, but the mechanisms involved in this process were not known. Now, an international team has clarified how SIRT1 is regulated during cellular senescence [1]. Cellular...
November 12, 2018
Today, we want to highlight a new study that used in silico analysis to look at the interaction between metformin and SIRT1 [1]. SIRT1 and metabolism Silent mating type information regulation 2 homolog (SIRT1) is a member of the sirtuin protein family, and studies suggest that human sirtuins act as intracellular regulatory proteins. Sirtuin 1...
March 23, 2018
A team of Harvard Medical School scientists led by Dr. David Sinclair has successfully reversed the aging of blood vessels in a new study, and human trials are currently underway. The therapy restores blood vessel growth and muscle vitality and boosts exercise endurance in aging animals. Age-related muscle wastage is linked to vascular aging The...