PCBrainAge | Lifespan.io

April 27, 2022

An Epigenetic Clock for Brain Age and Alzheimer’s Disease

The risk of Alzheimer’s disease goes up with age, and the number of people living with Alzheimer's is growing. While it is known to be associated with the loss of proteostasis, it has also been found to be associated with epigenetic alterations. An advanced online preprint in bioRxiv was published by Dr. Morgan E. Levine...

Developing a Treatment for Arthritis from Stem Cell Signals
Resarchers publishing in Aging have found that extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (MSCs) reduce inflammatory markers in chondrocytes, which are responsible for building and maintaining human cartilage. An established […]
Creating a Noise Clock to Measure Biological Age
Publishing in Aging, the Conboy research lab has outlined the problems with existing machine learning-based clocks and created a new clock based on epigenetic noise. The problem with linear regression This paper begins with […]
EARD2023: Using NFTs to Support Video Gaming for Good
In this talk, Lifespan.io President Keith Comito describes use cases for “Proof of Philanthropy” (PoP) dynamic NFTs – a new type of NFT that powers up based on tracked on-chain giving. These NFTs, built on the Polygon […]
Senolytics as a Potential Back Pain Treatment
In a recent paper, researchers from McGill University in Canada have investigated how a combination of two senolytics, RG-7112 and o-Vanillin, influences the intervertebral disc cells of back pain patients [1]. Back pain is […]
A Potential Exercise Mimetic to Restore Youthful Memory
Researchers have identified a platelet-derived factor that improves cognition in mice and published their findings in Nature Communications. Finding the right molecules This paper begins with the same refrain common in discussions about the […]

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An Epigenetic Clock for Brain Age and Alzheimer’s Disease