Help us: Donate
Follow us on:
×

Menu

Back

Tag: Partial Cellular Reprogramming

Muscles in motion
Boosting the expression of the transcription factor NANOG reduces markers of cellular senescence in cultured muscle cells and in live mouse models, according to new research [1]. This holds out the hope that cells could be rejuvenated without reprogramming them to pluripotency, avoiding some of the associated risks such as oncogenicity. However, some of the...
Hidden information
A new company focused on aging has launched, and it has the backing of Yuri Milner and Jeff Bezos among other wealthy people interested in tackling aging. Altos Labs is founded to treat aging itself In recent months, there have been some hints but considerable secrecy surrounding the formation of a new aging research company...
Press the reset button
Today, we chronicle the progress of partial cellular reprogramming and discuss how this powerful treatment may be able to reprogram cells back into a youthful state, at least partially reversing epigenetic alterations, one of the proposed reasons we age. We have created an introduction video about cellular reprogramming and if you would like to learn...
computational biology
In a preprint paper, scientists from Calico, Google’s longevity research behemoth, suggest that contrary to our previous understanding, transient reprogramming of cells using Yamanaka factors involves suppressing cellular identity, which may open the door to carcinogenic mutations. They also propose a milder reprogramming method inspired by limb regeneration in amphibians [1]. Rejuvenation that can give...
Journal Club
The journal club is back for December and we will be discussing the new Sinclair lab paper where researchers have successfully rejuvenated the eyes of aged mice using cellular reprogramming. As some additional background, we recently covered the paper in an article on the news outlet which you can find here. Join us December 22nd...
Journal Club
The Journal Club with Dr. Oliver Medvedik returns on November 24th at noon EST and will be livestreamed on our Facebook page. The topic this month will be a new study in which researchers have again demonstrated that it is possible to reverse aspects of aging in the old cells of a living animal, not...