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Tag: Partial Cellular Reprogramming

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March 08, 2021
Today, we chronicle the progress of partial cellular reprogramming and discuss how this powerful treatment may be able to reprogram cells back into a youthful state, at least partially reversing epigenetic alterations, one of the proposed reasons we age. For those of you new to the subject of epigenetic alterations you can learn more by...
Journal Club
December 10, 2020
The journal club is back for December and we will be discussing the new Sinclair lab paper where researchers have successfully rejuvenated the eyes of aged mice using cellular reprogramming. As some additional background, we recently covered the paper in an article on the news outlet which you can find here. Join us December 22nd...
Journal Club
November 05, 2020
The Journal Club with Dr. Oliver Medvedik returns on November 24th at noon EST and will be livestreamed on our Facebook page. The topic this month will be a new study in which researchers have again demonstrated that it is possible to reverse aspects of aging in the old cells of a living animal, not...
October 26, 2020
Today, we want to highlight another study that takes us a step closer to getting partial cellular reprogramming to the clinic. Partial Cellular ReprogrammingDrs. Takahashi and Yamanaka showed that they could use Oct4, Sox2, Klf4, and c-Myc (OSKM) to reprogram cells back to pluripotent, embryonic stem cells. While this discovery showed that cellular identity and aging could...
Birthday cake
June 07, 2019
Not so long ago, it was my 44th birthday, and I've finally decided to write something that I've been reflecting on for a while. To some people, a birthday is a cause for celebration; for others, it is viewed as a bad thing. Yes, if you take the negative view, you could see it as...
March 20, 2019
We have talked about the potential of partial cellular reprogramming in previous articles, and today, we want to draw attention to a new paper that promises to further refine reversal of epigenetic aging in cells. As we age, our cells experience alterations to their epigenetic markers, and this changes gene expression, which is proposed to...