May 16, 2025
What is aging? Sadly, we don’t know. If we ask the experts in the field, they will give us different answers [1]. Consensus has not been reached on even the trivial definition of aging, let alone its primary mechanisms. But, can we cure aging without understanding it? I think not. Knowledge is essential to target...
May 01, 2025
For most of the history of human civilization, humanity expanded at an astonishing pace: faster than exponential, nearly hyperbolic. This trend was famously described in a 1960 paper by Heinz von Foerster and colleagues, who extrapolated global population data to predict a so-called "Doomsday", a demographic singularity in which human numbers would become infinite by...
February 24, 2025
No other human endeavor today holds more promise than understanding and targeting aging. The molecular mechanisms that drive aging impact overall vigor, environmental stress resistance, reproductive health, and broad disease risk, and they fundamentally change what life means by radically changing our relationship to death. Intriguingly, aging mechanisms are highly evolutionarily conserved, so much so...
September 18, 2023
In the Proceedings of the National Academy of Science, Dr. Jesse Poganik and Prof. Vadim Gladyshev of Harvard Medical School have presented an opinion proposing a consensus understanding of aging. A problem of focus and funding The authors lament a lack of focus and funding in the field of gerontology, noting that a full 60%...
April 02, 2021
The good news is that the United States Senate has a Special Committee on Aging. The bad news is that it has little to do with the actual processes of aging and has not meaningfully furthered the research necessary to develop medical treatments for aging itself. Instead, the committee focuses its work on other issues...
January 29, 2021
Do members of Congress actually listen to the concerns of their constituents? Are the letters and emails you send read, or are they discarded into the physical or virtual trash? If they are read, does it even make any difference? Popular belief would tell you that the answer is no to all of the above,...
