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Tag: Neurodegenerative Diseases

Neuron Connections
Researchers have identified an important mechanism of neurodegeneration that may be useful in treating age-related diseases such as Alzheimer’s and dementia [1]. These neurons must die Age-related neurodegenerative diseases, including Parkinson’s and Alzheimer’s, have become more prevalent mostly because of the successes of modern medicine. Today, more people become old enough to fall prey to...
Rat in maze
Researchers from Hebei Medical University in China have found that testosterone supplementation ameliorates age-related brain dysfunction in male rats. A focus on mitochondria Why we Age: Mitochondrial DysfunctionAs they age, the mitochondria in our cells lose their ability to provide cellular energy and release reactive oxygen species that harm cells and cause increasing levels of...
Neurons
A new study shows that functional deterioration of the nervous system contributes to late-life mortality and identifies a related bloodborne biomarker for all-cause mortality [1]. Neurofilament light chain (NfL) is a structural protein found in nerve cells. The nervous system has been implicated in aging and longevity, so the fact that NfL can be detected...
Mouse facing camera
A group of scientists have shown that the SIRT2 protein increases the accumulation of amyloid beta, a known marker of Alzheimer's disease (AD), in the brains of mice. They propose a mechanism underlying this phenomenon and demonstrate that inhibiting SIRT2 ameliorates AD-associated cognitive decline in mice [1]. AD is one of the most devastating age-related...
Oxytocin in hearts
Japanese researchers led by Professor Akiyoshi Saitoh from the Tokyo University of Science have published new research that explores the potential of oxytocin as a therapy to combat cognitive disorders such as Alzheimer's disease. Oxytocin is often called the love hormone, given its role in the reproductive system and its role in creating feelings such...
Scientists at Scripps Research have developed a new screening platform that has allowed them to identify a new set of compounds that appear to have a potent protective effect on the mitochondria of brain cells, helping these cells to defend against the kinds of stresses encountered during Alzheimer's disease and other neurodegenerative conditions. Improved screening...