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Tag: Mitochondrial Dysfunction

Brain regions
In a new study published in Free Radical Biology and Medicine, researchers have identified a link between mitochondrial function and the vulnerability of specific brain regions to age-associated neurodegeneration [1]. Brain region-specific vulnerability It is well-known that the human brain is heterogeneous in terms of structure and function. The prefrontal cortex is responsible for complex...
Exercising people
Researchers publishing in BMC Medicine have found that there is a relationship between biomarkers of aging and measurements of health and mental well-being [1]. "Healthy lifestyle" is not just a phrase It is very well known that unhealthy behaviors are strongly linked to adverse health outcomes. For example, alcoholism is a significant risk factor for...
Microplastics
A paper published in Environmental Science and Technology has described some of the effects of nanoplastics on human liver and lung cells [1]. Microplastics and nanoplastics Plastics in the environment are gradually broken down by sunlight, grinding processes, and biological activities into smaller and smaller pieces [2]. These are the infamous microplastics, but when they...
Dividing cell
Researchers publishing in Cell Stem Cell have found that the mitochondrial protein OPA1 is an integral, regulatory part of muscle stem cell activation, the process by which muscle stem cells proliferate and become active muscle tissue (myogenesis) [1]. Another piece of the puzzle We have recently reported on the effects of mitochondrial fusion and fission...
Smooth muscle
A paper published in Cell Stem Cell has detailed how mitochondrial division is critical to the ability of muscle stem cells to regenerate damaged tissue [1]. Waiting until needed This paper begins with a discussion of quiescent muscle stem cells, which are held in reserve until injury causes them to form new somatic muscle cells,...
Genes computer
Publishing in GeroScience, a team of researchers that included Nir Barzilai and Matt Kaeberlein examined genes that may affect both mitochondria and lifespan [1]. From the mitochondria to the nucleus Over time, evolution has moved mitochondrial DNA from the individual mitochondria to the nucleus, where they are better protected. SENS Research Foundation, in conjunction with...