January 18, 2024
A recent study published in GeroScience has investigated whether or not a common index of metabolic syndrome can be applied to chronic kidney disease (CKD). A common metric of diabetes The triglyceride-glucose (TyG) index, which is calculated from fasting triglyceride and glucose, is used as a surrogate for insulin resistance [1], a key characteristic of...
June 27, 2023
For the first time in history, scientists have been able to freeze, preserve, rewarm, and transplant rat kidneys with a new method of organ cryopreservation [1]. The rewarming problem Today, organ transplantation is severely limited by the fact that organs can only be preserved for a short time in near-freezing temperatures. Long-term cryopreservation of...
March 23, 2022
A cohort study that was published in BioMed Central by Dr. Alsayyari and colleagues examined fasting on acute kidney injury incidence [1]. Background Fasting during the month of Ramandan is a obligation in Islam with exceptions, such as for chronic illness that has a poor prognosis or is uncontrolled [2]. Our prior articles discuss the...
March 01, 2022
Scientists have shown that chloroquine, a well-known anti-malarial drug and the cousin of hydroxychloroquine, attenuates inflammation and fibrosis while significantly extending median and maximum lifespan in naturally aged rats [1]. Fighting malaria since 1934 Chloroquine (CQ) was developed back in 1934 as an anti-malarial treatment and as such has enjoyed significant success. Since 2020, an analog...
December 13, 2021
Researchers publishing in Aging Cell have discovered how and why oleuropein (OLP), a polyphenol derived from olives, ameliorates epigenetic kidney aging. KidneyThe kidney's main function is to filter waste products out of the blood and deliver the resulting urine to the bladder. The functional unit of the kidney is called the nephron, and each kidney...
October 07, 2021
Publishing in Aging, a team of researchers has reported that periostin, a protein that aids in development during the embryonic stage, is linked to kidney problems related to lipid metabolism in adults. KidneyThe kidney's main function is to filter waste products out of the blood and deliver the resulting urine to the bladder. The functional...