Help us: Donate
Follow us on:
×

Menu

Back

Tag: Inflammaging

Strong mouse
In their publication in Stem Cell Research & Therapy, a team of researchers has shown how effective mesenchymal stromal cells (MSCs) are in a mouse model. Multipotent cells with multiple uses As multipotent stem cells, MSCs can differentiate into several different cell types, including fat cells, neurons, and bone cells [1]. The researchers point to...
Manhattan plot
Nature Communications has recently published a paper discussing the genetic sources of C-reactive protein, a well-known biomarker of chronic inflammation. What is Inflammaging? Chronic Inflammation and AgingThe aging process is accompanied by a chronic, smouldering background of inflammation that researchers call “inflammaging”.Read More An extremely broad study with a wide variety of genes Pulling genomic...
Mouse in a swim test.
In a new study, genetic deletion of the TLR4 receptor ameliorated aspects of age-related cognitive decline in naturally aging mice, probably due to decreased inflammation [1]. Taking a toll as we age Toll-like receptor 4 (TLR4) is a member of an ancient, highly evolutionary conserved family of proteins expressed mostly by the cells of the...
Healthy Diet
In a population study, scientists have found that consuming foods associated with a low Diet Inflammatory Index substantially lowers the risk of dementia [1]. Aging is accompanied by an increase in chronic, low-grade inflammation, known as inflammaging, which has been linked to multiple age-related diseases. Inflammaging promotes cancer, diabetes, cardiovascular diseases, and various types of...
Champions of Coronavirus
A research paper that has just been peer reviewed and published in Nature has described how disrupting an immune pathway that is upregulated in aging decreases the lethality of COVID-19 in a mouse model. Mice with COVID-19 As the researchers explain, normal mice do not use the same angiotensin converting enzyme 2 (ACE2) as humans,...
Microglia
Scientists show that when done right, partial elimination of microglia, the immune cells of the brain, lowers age-related inflammation and cellular senescence [1]. Aging makes microglia bitter Brain health is of utmost importance for geroscientists, since the brain is the one organ that cannot be replaced, and microglia are the brain's resident immune cells. Reacting...