August 24, 2021
In a study published in Genome Biology, researchers explain how they are working to make CRISPR less prone to large, accidental deletions of genetic material [1]. A previously unknown large problem While this seems counterintuitive, previous technology only allowed for the ready identification of deletions below 100 base pairs. New technology has allowed for larger...
July 15, 2021
Gene editing can make stem cells invisible to the immune system, making it possible to carry out cell therapy transplants without suppressing the patients' immune response [1]. Help me help you Cellular therapies involve transplanting cells into a patient to replace the activity of malfunctioning or damaged cells. For example, cardiomycetes could be transplanted to...
April 23, 2021
The Journal Club hosted by Dr. Oliver Medvedik will return live to our Facebook Page at 12:00 EST on Tuesday 27th of April. This month we will be taking a look at a new paper and technique for the gene editing tool CRISPRcas9. The technique allows researchers to turn epigenetic methylation off and back on...
September 08, 2020
A group of researchers has used CRISPR to create energy-dissipating brown adipocytes (fat cells) from white preadipocytes. The new cells were then shown to alleviate obesity in mice [1]. Obesity: the nemesis of longevity Obesity is one of humanity’s deadliest enemies. It is a known comorbidity in a plethora of diseases, including age-related, such as...
March 31, 2020
Researchers have overcome a major limitation of the CRISPR-Cas9 gene editing system, which should allow previously inaccessible parts of the genome to be edited with ease. What is CRISPR-Cas9? Clustered regularly interspaced short palindromic repeats (CRISPR) is used in CRISPR-Cas9 and CRISPR-associated protein, a gene editing system that has created considerable excitement in the last...
November 25, 2019
A new study recently accepted by iScience has shown that a specific genetic alteration can selectively remove pluripotent stem cells from stem cell therapies in order to purify them for use in treatment. The cells we don't want As we age, our stem cells both decrease in number and become less efficient in replenishing somatic...
