September 22, 2023
Resarchers publishing in Aging have found that extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (MSCs) reduce inflammatory markers in chondrocytes, which are responsible for building and maintaining human cartilage. An established approach This is far from the first attempt at treating osteoarthritis using stem cells. We have previously reported on a...
September 18, 2023
The Journal Club returns with Dr. Oliver Medvedik on September 29th at 12:00 Eastern time on our Facebook page. We take a look at a recent study published in Nature, in which extracellular vesicles derived from neonatal cardiac progenitors produced significant rejuvenation in old rats and human cells. Abstract Rejuvenation of an old organism was...
September 01, 2023
In a new study published in Nature, extracellular vesicles derived from neonatal cardiac progenitors produced significant rejuvenation in old rats and human cells [1]. Tiny messengers Extracellular vesicles (EV) are microscopic bubbles encased in the same lipid bilayer that cellular membranes are made of. EVs are secreted by cells, and they carry various molecular cargo...
August 15, 2023
Scientists have found that bubbles secreted by embryonic stem cells counter cellular senescence, in large part due to just two tiny snippets of RNA [1]. Helpful bubbles Extracellular vesicles (EVs) are membrane-bound tiny bubbles that are loaded with various molecular cargo, such as proteins, DNA, or RNA, that cells secrete as a method of intercellular...
March 28, 2023
Scientists have shown that extracellular vesicles derived from senescent stem cells can improve the proliferation, viability, and migration capacity of healthy stem cells [1]. Cell-to-cell packages Extracellular vesicles (EVs, not to be confused with electric vehicles) are tiny membrane-bound bubbles that are emitted by cells and carry various molecular cargo such as proteins and miRNA....
March 06, 2023
A review paper published in Cells has described multiple ways in which the secretion of extracellular vesicles (EVs) changes with aging, leading the authors to propose it as its own hallmark. Extracellular vesicles and their uses This review begins with an outline and explanation of extracellular vesicles and their classifications. Cells use extracellular vesicles to...