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Tag: Epigenetic Alterations

Exercise clock
A new, three-year study published in The Journals of Gerontology: Series A examined the relationship between epigenetic clocks and physical performance in older women. Epigenetic clocks and biological age  Epigenetic Clocks - What are they?An epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA to determine...
Levine Interview
In her lab at Yale, Dr. Morgan Levine tackles some of the most exciting and difficult problems in geroscience. She specializes in bioinformatics and is working on creating and finessing clocks that measure biological age. We talked with Dr. Levine about her work, the impact that biological age clocks have had on the longevity field,...
Bone structure fails as we age but can be rejuvenated
Researchers have shown that age-related loss of bone maintenance is caused by changes in gene expression [1]. Perhaps most importantly, those changes can also be reversed and the bone marrow stem cells rejuvenated. Bones become weaker as we age as stem cell function declines With advancing age, it is typical for our bones to become...
Steve Horvath at EARD2021
In his talk at Ending Age-Related Diseases 2021, Steve Horvath discussed a cytosine-based, pan-mammalian epigenetic clock that works across a wide variety of species. He also discussed how several of the hallmarks of aging do not seem to have any effect on epigenetic alterations.  Script Hello, thank you for your interest. My name is...
Hidden information
A new company focused on aging has launched, and it has the backing of Yuri Milner and Jeff Bezos among other wealthy people interested in tackling aging. Altos Labs is founded to treat aging itself In recent months, there have been some hints but considerable secrecy surrounding the formation of a new aging research company...
Press the reset button
Today, we chronicle the progress of partial cellular reprogramming and discuss how this powerful treatment may be able to reprogram cells back into a youthful state, at least partially reversing epigenetic alterations, one of the proposed reasons we age. We have created an introduction video about cellular reprogramming and if you would like to learn...