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Tag: Epigenetic alterations

September 11, 2020
Today, we have something a little bit different: progress in aging biomarkers but, this time, for cats! The race has been on for some years now to create biomarkers that can accurately measure biological age. Having such biomarkers is critical in the development of therapies that target the aging processes directly, and one of the...
August 14, 2020
A novel treatment that inhibits the activity of the Cdc42 protein has been found to extend the lifespan of aged mice, most likely through epigenetic changes and regulation of inflammatory cytokines. Cdc42 is linked with lifespan Cdc42 is a RhoGTPase, a kind of signaling protein involved in a variety of processes in eukaryotic cells. It...
August 10, 2020
Epigenetic alterations, which are one of the proposed reasons we age, are the changes to gene expression that our cells experience as we get older. These alterations harm the fundamental functions of our cells and can increase the risk of cancer and other age-related diseases. Depending on your view, epigenetic alterations are either the result...
July 24, 2020
A team of researchers have developed a tissue-specific clock that can measure the biological age of skin. There is plenty of new evidence that different organs and tissues in our body age at different rates. In particular, the epigenetic state, the pattern of gene expression, of the cells that comprise these different organs and tissues...
July 16, 2020
A new perspective published in Cell explains a direct link between genomic instability, one of the primary hallmarks of aging, and age-related diseases. Somatic mutations Mutation is normally explained as the driving force behind evolution, as changes in the germ lines of organisms result in beneficial and harmful mutations to organisms. The organisms with the...
May 25, 2020
As we previously announced, this session of Journal Club features Dr. Oliver Medvedik presenting a new study in which researchers claim that they have halved the epigenetic age of old rats using blood factors present in young rats. (adsbygoogle = window.adsbygoogle || []).push({});