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Tag: Epigenetic Alterations

Alzheimer's MRIs
The risk of Alzheimer’s disease goes up with age, and the number of people living with Alzheimer's is growing. While it is known to be associated with the loss of proteostasis, it has also been found to be associated with epigenetic alterations. An advanced online preprint in bioRxiv was published by Dr. Morgan E. Levine...
Guinea pig
Publishing in Aging, a team of researchers has explained the relationship between tuberculosis (TB) and multiple aspects of aging, including epigenetic alterations and the senescence-associated secretory phenotype (SASP). A disease known to cause long-term harm Tuberculosis, a disease that has proliferated around the world, kills 1.4 million people every year. Previous research has shown that,...
Rainbow Clocks
In a preprint published in bioRxiv, Morgan Levine and colleagues have identified and grouped 5,717 epigenetic CpG sites into 12 different modules, conducting an in-depth examination into how epigenetic clocks work. Epigenetic Clocks - What are they?An epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA...
Work Stress
A study published in Aging that studied the Northern Finland Birth Cohort of 1966 has found some interesting and counterintuitive results regarding work stress and accelerated epigenetic aging. Work stress is widely associated with premature death It is common folk wisdom that too much stress leads to a shorter lifespan, and this belief has been...
EARD2021 Irina Conboy
At Ending Age-Related Diseases 2021, Irina Conboy discussed the effects of plasma dilution and heterochronic plasma exchange and their relationship to epigenetic alterations. Script Thank you for inviting me again, it's much appreciated. This is an excellent conference series. I will start by telling you that it is my deep belief that the path to...
Naked mole rat
A research paper published in Nature by Dr. Vadim Gladyshev and his team has investigated the epigenetic aging of the naked mole rat, an animal whose mortality rate does not appear to increase with age. Why we Age: Epigenetic AlterationsEpigenetic alterations are age-related changes in gene expression that harm the fundamental functions of cells and...