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Tag: DNA

Egg cell
A group of researchers has documented in Aging that Epitalon, a synthetic peptide made of four amino acids, slows the aging of egg cells (oocytes) after ovulation. Aging makes fertilization difficult Oocyte aging is well-known to lead to fertilization deficiencies and a host of other problems that are visible in the cells themselves, including abnormalities...
Skin aging
A group of researchers successfully alleviated aspects of skin aging by treating skin cells with the NAD precursor nicotinamide [1]. Hard work done by skin leads to its burnout Skin aging might not be lethal, apart from the increased risk of skin cancer, but it's surely conspicuous, frustrating, and emblematic of organismal aging. Being our...
Broken DNA
A review published in Frontiers in Cell and Developmental Biology has explained how DNA damage and its accompanying immune response lead to changes in the microenvironment of stem cells, causing a decline in their function. Why we Age: Stem Cell ExhaustionStem cell exhaustion is the age-related deficiency of stem cells. This particular hallmark is directly...
Chromosome
A new study in Nature Genetics has further illuminated the genetic regulation of telomere length and what implications it may have for various diseases and longevity. Telomeres and aging in humans Why We Age: Telomere AttritionTelomeres are DNA regions located at the ends of a chromosome. Their normal length is 8-10 thousand base pairs, yet...
Breast cancer
Cells from the breasts of women with mutations that increase their risk of breast cancer show signs of accelerated aging, according to new research [1]. Accelerated aging may make these cells worse at suppressing cancer development, offering both an explanation for the effect of these mutations and an unexplored path for possible treatments. Risky mutations...
Rendering of chromosomes
In a preprint paper, scientists have announced the completion of the first full, telomere-to-telomere, sequencing of the human genome, more than two decades after the first draft of its sequencing. This was made possible by new sequencing technologies [1]. Mind the gaps The human genome was first reported as being sequenced two decades ago by...

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