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Tag: Diabetes

Varied diet
Pitting a ketogenic diet against a Mediterranean diet in pre-diabetes and Type 2 diabetes patients, scientists have learned that both confer metabolic benefits, but "keto" also has a darker side [1]. Diabetes is often reversible with diet While many anti-diabetes drugs have been developed in recent decades, with some being repurposed as anti-aging drugs [2],...
Lab mice
Scientists have found that canagliflozin, an anti-diabetes drug that is known to extend lifespan in mice, alleviates an array of age-related pathologies, albeit in males only [1]. Anti-diabetes and anti-aging Canagliflozin, a widely used anti-diabetes drug, belongs to the class of sodium glucose cotransporter 2 (SGLT2) inhibitors, which regulate glucose reabsorption by the kidneys. Recently,...
Hands together mouse
Scientists have found that rapamycin and metformin work hand in hand in diabetes-prone mice, boosting each other's effectiveness and blocking side effects [1]. The combination hypothesis Rapamycin and metformin are probably the two most promising anti-aging drugs known. Both have been in use for various indications for decades and have decent safety profiles. However, there...
Weight Loss
A large Phase 3 study published in the New England Journal of Medicine shows that an existing drug combined with a healthy diet and mild exercise leads to an average weight loss of 20% [1]. Diet and exercise are not always enough Being a known comorbid factor in many diseases of aging, obesity is tightly...
Sunlight
New data has been released from the Vitamin D Type 2 Diabetes (D2d) study [1]. This study is a randomized, controlled trial that includes overweight and obese people studied at 22 academic medical centers in the United States. This data was collected between October 2013 and February 2017. After screening procedures and inclusion criteria, 2423...
Blood pressure
An advance online preprint was recently released in Circulation Research examining carotid bodies' role in hypertension and diabetes [1]. It will be published in the journal later this week. Drugs that target the glucagon-like peptide 1 (GLP1) receptor are widely used to treat type 2 diabetes and have also been well-documented for their cardiovascular and...