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Tag: Diabetes

Alpha-lipoic acid (also known as ALA) is a common supplement, and we take a look at it in the context of aging. What is alpha-lipoic acid? Alpha-lipoic acid is an organosulfur (an organic compound that contains sulfur) derived from caprylic acid (also known as octanoic acid). It was first discovered in 1937, when Snell found...
Muscle fibers
In recent years, there has been considerable interest in the naturally occurring molecule and dietary supplement nicotinamide mononucleotide (NMN) and its potential influence on aging. While there have been numerous animal studies suggesting that it may be useful in combating some age-related decline, there has been a lack of human data until now. In previous...
Welcome to part two of a two-part series exploring NAD+ biology; you can find part one here. There are already a myriad of excellent reviews on NAD+ biology in general [1-3], so, in this article, we will be mainly focusing on the NAD+ precursor nicotinamide mononucleotide (NMN). NMN and synthesis of NAD+ NMN can be...
A recent study published in Cell Metabolism has shown that metformin, a drug that has been previously shown to be effective against some aspects of aging, ameliorates inflammaging by promoting autophagy, the cellular recycling of damaged components. Mitochondrial dysfunction, autophagy, and TH17 Mitochondrial dysfunction is one of the hallmarks of aging, the root causes that...
Retina
Researchers from Johns Hopkins Medicine have successfully used stem cells to repair diabetic damage to retinal blood vessels. The researchers believe that their findings will advance regenerative approaches that seek to reverse conditions such as diabetic retinopathy and other eye diseases that lead to blindness. Induced pluripotent stem cells (iPSCs) have been around for well...
Healthy family
According to a new study from Harvard researchers, switching to a healthier lifestyle by the time you reach middle age could potentially give you eight to ten more years of healthy life free from age-related diseases. Healthy habits mean a longer, healthier life This new epidemiological study shows that adopting the five habits of eating...