Tag: Cognitive Decline

New research suggests that digital technologies provide beneficial effects on cognition in middle-aged and older adults who did not grow up with such technologies [1]. Childhood without computers For younger people, it is difficult to imagine living in a world without the internet and digital technologies. However, older people grew up in a world without...

Using a mouse model, researchers from UCSF have found that the genes that become activated on the silent X chromosome might explain some sex-dependent differences in cognitive abilities during aging [1]. XX and XY It is widely known that women live longer than men [2]. Women also show differences in cognitive aging [3]. "In typical...

In Aging Cell, researchers have established a link between cellular senescence and cognitive decline in unmodified male mice. Resilience versus decline The authors begin their paper by noting that cognitive decline in older people varies greatly. Some people suffer serious cognitive defects; other people are scarcely impacted at all [1]. The researchers have developed an...

Yesterday in Aging Cell, researchers published their findings that using gene therapy to overexpress a synaptic promoter increases cognitive ability in ordinary, middle-aged mice. Hevin vs. SPARC Astrocytes are general-purpose helper cells of the brain, and one of their tasks is to maintain synapse structure [1]. They secrete synapse-modifying molecules, including members of the SPARC...

A reanalysis of data from a previous study identified a difference between people with low and high levels of inflammatory biomarkers. The cognitive performance of people with high levels of inflammation improved after they consumed anthocyanin supplements [1]. Inflammation and dementia Dementia is a complex disorder that involves multiple biological processes, including neuroinflammation. Previous research...

Neurological researchers, in Aging Cell, have deepened our understanding of the brain, explaining how turning off a dopamine receptor may lead to better memory in older people. Sometimes it's better for the dopamine not to hit With aging comes changes in how the brain processes dopamine [1]. This work focuses on specific dopamine receptors called...