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Tag: Cellular Senescence

Coughing
A study published in Aging Cell has shown that senescent cells impact the way that CD4 T cells differentiate into types and that senolytics can restore this differentiation to a more youthful one. Not all T cells are the same CD4 T cells, often known as helper T cells due to their recruitment and signaling...
Vaccination
The journal Nature has published a letter communication regarding a senolytic vaccination study [1]. These letters are typically research studies that the editor chooses to urgently publish due to the importance they hold for the other researchers in the field. They may or may not be peer reviewed before this publication. Background Why we Age:...
Old and Young Mice
A new publication in Aging Cell has found divergent results between the post-injury muscle regeneration of young and old mice treated with senolytics [1]. Senescent cells: Friend or foe for muscle regeneration? Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which...
Raw hot peppers are a source of quercetin.
Found in many fruits and vegetables, quercetin may have some potential in the context of aging. Here, we take a look at this natural antioxidant and popular dietary supplement. What is quercetin? Quercetin is a natural flavonoid, which makes it part of a large family of water-soluble plant compounds. Flavonoids are not created by the...
Grape seeds
Studying grape seed extract, scientists have discovered a new senomorphic compound that enhances chemotherapy and prolongs lifespan and healthspan in mice [1]. Nature's drugstore Many drugs have come to us from the world of plants, including promising geroprotective molecules such as resveratrol. However, identifying specific components of plant extracts that exert positive effects can be...
Stroke
The newest study published in the International Journal of Molecular Sciences investigates the role senescent cells may play in cerebral ischemia-reperfusion injury and how senolytic therapy may be beneficial for those recovering from stroke. Stroke and reperfusion injury Ischemic stroke occurs when an artery in the brain is occluded, preventing an area of brain tissue...