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Tag: Cellular senescence

July 30, 2020
The well-known resistance of naked mole rats to aging and aging-related effects is due at least in part to an unusual ability to clear away senescent cells. This suggests that senolytic drugs, which aim to do the same in humans, may prove a fruitful path to longevity. Naked mole rats live much longer than other...
June 24, 2020
In a recent study, researchers from the Buck Institute have shown that cellular senescence, one of the hallmarks of aging, is partially responsible for Alzheimer's disease. Cellular senescence As you age, increasing numbers of your cells enter into a state known as senescence. Senescent cells do not divide or support the tissues of which they...
June 23, 2020
Could the immune system itself be the best way to purge senescent cells, which accumulate as we age, from the body? A new review takes a look at the role of the immune system in removing these problematic cells. What are senescent cells? As you age, increasing numbers of your cells enter into a state...
June 22, 2020
Researchers are starting to test the use of immunotherapies, normally used for treating cancer, to target senescent cells, which accumulate in our bodies as we age and are implicated in many age-related conditions. What are senescent cells? As you age, increasing numbers of your cells enter into a state known as senescence. Senescent cells do...
June 15, 2020
Senescent cell accumulation is a likely reason we age, but removing some populations of specialized cells that have turned senescent may have negative consequences, according to a new study. What are senescent cells? As you get older, more and more of your cells enter into a state known as cellular senescence. Senescent cells no longer...
May 28, 2020
The Human Ageing Genomic Resources (HAGR) is a collection of curated databases and tools designed to help researchers study the genetics of human aging through modern approaches such as functional genomics, network analyses, systems biology and evolutionary analyses. One of the many databases in the HAGR family is CellAge, which contains information about 279 genes...