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Tag: Cellular Senescence

Columbia sheep
A study published in Antioxidants has found that the senolytic fisetin significantly decreases cellular senescence in the brains of sheep. A flavonoid with a long history Fisetin: Benefits, Side Effects, and ResearchFisetin is a plant polyphenol and part of the flavonoid group in the flavonol sub-category. It is present in many trees and plants, including...
Gene analysis
A paper published in GeroScience has described a gene responsible for a key biomarker of cellular senescence. A widely used biomarker Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead, they emit potentially harmful chemical...
Scientists have found that bubbles secreted by embryonic stem cells counter cellular senescence, in large part due to just two tiny snippets of RNA [1]. Helpful bubbles Extracellular vesicles (EVs) are membrane-bound tiny bubbles that are loaded with various molecular cargo, such as proteins, DNA, or RNA, that cells secrete as a method of intercellular...
Ginkgo Biloba
Researchers publishing in Aging Cell have documented some potential effects of rutin against senescence and cancer. Rutin is a natural compound found in several plants. Another compound to fight senescence In this study, the researchers place rutin among the many other natural compounds that have demonstrated effectiveness in the lab against cellular senescence, including fisetin...
Sarcopenia
Researchers publishing in Aging Cell have documented a human clinical trial showing that metformin reduces atrophy caused by long periods of bed rest. A common problem and a well-known diabetes drug Long periods of disuse cause muscles to atrophy and accelerate the age-related muscle wasting known as sarcopenia [1]. Strength training is the accepted treatment...
Smoking mouse
Researchers publishing in Aging Cell have described how treating the increased senescent cell burden that comes with cigarette smoke exposure can repair some of the damage. Senescent cells and COPD Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which...