Help us: Donate
Follow us on:
×

Menu

Back

Tag: Cellular Senescence

Glioblastoma
A report in the Journal of Cell Science has outlined different stages of cellular senescence alongside a mechanism that reverses it, along with a potential new treatment for glioblastoma. Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they...
Bad news
A study published in Aging has shown that inhibiting histone deacetylases (HDACs), an approach used for treating cancer and other diseases, can lead to cellular senescence. Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead,...
Fibrotic liver
A new study published in Aging has shown a link between a reduction in telomerase reverse transcriptase (TERT), the gene that allows for telomere maintenance, and the development of myofibroblasts, cells that are a part of organ fibrosis. It also documents the link between telomere attrition and cellular senescence, two of the hallmarks of aging....
Scientific Announcement
Leading the pack is never easy, but today, UNITY Biotechnology is back with some positive news for senolytics. Being first is not always easy UNITY Biotechnology is a company that has been developing senolytics for the removal of senescent cells, which accumulate with age, drive chronic inflammation, and spur various age-related diseases. Why we Age:...
Time restricted eating
Scientists have shown in mice that long-term caloric restriction can attenuate age-related immunosenescence on par with antibody-mediated clearance of senescent T-cells. On top of that, caloric restriction predictably improved glucose tolerance and lowered inflammation [1]. Senescent cells: inflamed and half-dead Immunosenescence is an umbrella term for a variety of largely detrimental changes that our immune...
Stem cell development
A new study published in the FASEB Journal shows how mesenchymal stem cells derived from adipose tissue (ADSCs) reverse some effects of aging in nearby cells. It's not the cells themselves, it's what they secrete The original and ongoing main purpose of stem cell therapies is to directly combat stem cell exhaustion: to replenish the...