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Tag: CD38

Chamomile is a great source of Apigenin.
April 16, 2021
Apigenin is a flavonoid, a compound found in various plants, and is the aglycone of several naturally occurring glycosides. It is solid and crystalline in structure with a yellow color to it. Apigenin can be found in many fruits and vegetables, but parsley, celery, celeriac, and chamomile, which is normally drank as a tea, are...
Complicated machinery
February 12, 2021
Aging is a multifactorial and complex process; indeed, it is probably the most complex disorder known. It is made up of a combination of dozens of malfunctions locked together in an accelerating spiral of decline. Despite this undeniable complexity, which is captured to some extent by grouping the many age-related dysfunctions into nine categories often...
CD38 protein image
December 08, 2020
We recently explored why NAD+ declines during aging, and today, we want to spotlight a new review that takes a deep dive into CD38, one of the reasons for this decline [1]. Nicotinamide Adenine DinucleotideNicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells. It is a dinucleotide, which means that it consists...
Inflamed knee
November 18, 2020
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living cells and is essential for cells to work; without it, life would be impossible. The connection between aging and the accompanying loss of NAD+ has been the subject of much research, and a new study sheds light on why this happens. Nicotinamide Adenine DinucleotideNicotinamide...
Diagram of NADH
July 23, 2020
There has been considerable debate around the age-related decline of NAD+, particularly regarding whether or not it occurs in humans as it does in other species, such as mice. Today, as part of a two-part special, we are going to be taking a look at some of the evidence for the age-related decline of NAD+...
Macrophage engulfing bacteria
April 15, 2020
Researchers have found that a protein called TIM-4 is essential to macrophages' ability to clean up cellular debris and that p38 MAPK, a protein that increases due to aging, inhibits TIM-4. Inflammaging and immunosenescence Aging is the primary risk factor for a myriad of chronic age-related diseases, including heart disease, Parkinson's, Alzheimer's, and cancer. As...