March 09, 2023
Research published today in Nature Aging has shown that heterochronic parabiosis, the circulatory joining of young and old organisms, has rejuvenative effects on the gene expression of multiple types of brain cells in mice. Parabiosis affects a wide variety of factors at once Heterochronic parabiosis is a well-known aging intervention in mouse studies, and some...
January 17, 2022
Publishing in GeroScience, a team of Oklahoma City researchers has found that a nitrone compound with a low molecular weight, OKN-007, maintains motor neuron functionality in the spinal cords of aging mice. Prior research OKN-007 is not new in the literature. This is a nitrone compound, which refers to a specific functional group in organic...
September 24, 2021
A study conducted in Sweden and published in Scientific Reports has outlined the relationship between aging and the metabolites present in cerebrospinal fluid (CSF), which cushions and supports the brain and spine. A detailed, metabolic analysis The researchers extracted CSF from 41 people aged 20 to 74 who don't have neurological disorders. They investigated somewhat...
September 07, 2021
A recent review published in Cureus shows why fecal microbial transplantation (FMT) might be able to help sufferers of Alzheimer's disease, showing how tightly the gut and brain are intertwined. Why would this ever work? The gut and brain are closely linked through biochemistry, and last month, we published an article about how the gut...
April 30, 2021
Research suggests that the degradation of the blood-brain barrier over time is a factor in the development of brain diseases. An organ we don't want to age As our brains age, we experience memory loss, a decreased ability to multitask, a lower attention span, and slower information processing [1, 2]. Severe diseases can occur as...
July 09, 2020
The mechanisms at work in the blood-brain barrier change with age, affecting the selectivity of this vital interface. The blood-brain barrier The blood-brain barrier is a layer of cells in the blood vessels of the brain that prevents molecules in the blood from crossing into the central nervous system. Selective transport across the barrier is...
