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Tag: atherosclerosis

January 30, 2020
Researchers from Stanford University and Michigan State University have teamed up to create a nanoparticle that can eat away at the arterial plaques that lead to strokes and heart attacks in a mouse model of atherosclerosis. The team has created a nanoparticle that acts like a Trojan horse, targeting atherosclerotic plaque to reduce its amount...
January 09, 2020
There are lots of exciting companies working in the aging field, and it's a great time to tell you about three of the more interesting ones. Most of these companies are a while away from human trials yet, but their innovations could possibly be truly game changing. Underdog Pharma Underdog Pharmaceuticals is a spin-off company...
December 04, 2019
For the December edition of the Journal Club hosted by Dr. Oliver Medvedik, we are joined by Dr. Matthew O' Connor (Oki) formerly of SENS Research Foundation and now the head researcher at Underdog Pharma, a spun-off biotech company that is developing research conducted at SENS into a hopefully viable solution for heart disease. Dr....
November 19, 2019
A particularly harmful byproduct of oxidized cholesterol appears to be a primary cause of atherosclerosis and a therapeutic target ripe for the taking. A new review takes a look at 7-ketocholesterol and its role in aging and disease. A new review exploring 7-ketocholesterol We recently reported on the launch of Underdog Pharma, a new startup...
November 14, 2019
Today, Underdog Pharma, a spin-off company of SENS Research Foundation, was officially launched with the lofty goal of eradicating atherosclerosis. Atherosclerosis is the leading cause of death worldwide and currently has no effective solution. Current medicine has three broad approaches towards it: lifestyle changes, such as diet and exercise; drugs that reduce the accumulation of...
November 11, 2019
A team of researchers from the University of Sheffield in the UK has identified a protein that plays a key role in the development of atherosclerosis, the leading cause of death worldwide. The trouble with Tribbles 1 Researchers have demonstrated for the first time that the protein known as Tribbles 1 (TRIB1) is expressed by...