Tag: Amyloid Beta

In a recent study, researchers identified the critical role that lithium plays in brain health and the development of mild cognitive impairment and Alzheimer’s disease. Supplementing with a lithium salt called lithium orotate can reverse many of its cognitive decline-related changes on the molecular and cellular levels [1]. The road less traveled Understanding the underlying...

Scientists have created engineered nanostructures that bind monomers and oligomers of harmful amyloid beta (Aβ) protein, preventing them from entering neurons and drastically increasing the cells’ survival in vitro [1]. Don’t let them into cells! Misfolded proteins are thought to be behind diseases like Alzheimer’s and amyotrophic lateral sclerosis (ALS). The most recognizable hallmark of...

An article in GeroScience describes a previously unexplored relationship between FABP7, an inflammatory molecule that binds to fatty acids, and Alzheimer's disease. Not just a transporter Originally, as the authors explain, fatty acid binding proteins (FABPs) were considered to be simple biological chaperones that did not perform biological functions. Further research found that they play...

In a study published in Cell Stem Cell, researchers have investigated a way to repopulate the brain with functional cells in order to fight back against Alzheimer's disease. A gene with a microglial function Various allelles of the apolipoprotein E (APOE) genes are well-known for their contributions to, or defenses against, Alzheimer's, as they affect...

  One of the most common diseases in the world is herpes, as 50 to 80% of Americans have this illness. The herpes simplex virus, which causes cold sores, is normally transmitted through person-to-person contact. This illness leaves the patient with blisters clustered around the mouth. Gradually, the blisters pop and leave sores that take...

Chinese scientists have found that the liver removes amyloid-β from circulation in mice, which also decreases its levels in the brain. The age-related impairment of this process might offer a new clue for fighting Alzheimer’s disease [1]. The janitor of the body Despite the flop-laden history of the amyloid-β-centered approach to Alzheimer’s, there is still...