Month: September 2023

A new study suggests that waist-to-hip ratio (WHR) has a more linear correlation with all-cause mortality than either body mass index (BMI) or fat mass index (FMI) and might replace BMI as a metric of choice [1]. Is BMI good enough? Comparing total mass to height, the body mass index (BMI) metric has become the...

In a recent article in Nature, researchers have restored cardiac regeneration to adult mice by disabling fatty acid oxidation, discovering a potential pathway for human treatments. A question of metabolism As heart muscle cells (myocytes) mature, they make a metabolic switch from glycolysis to the oxidation of fatty acids. Previous research has found that this...

In a recent paper, researchers reviewed the literature for human clinical trials that address NMN's safety and anti-aging effects [1]. The roles of NAD+ and NMN in aging Nicotinamide mononucleotide (NMN): Benefits and Side EffectsNicotinamide mononucleotide (NMN) is a precursor of the coenzyme NAD+, which serves critical functions in our cells. The decline of NAD+...

On this episode of Lifespan News, Ryan O'Shea ruminates on Elon Musk's statement on living forever being a curse rather than a blessing. Script Elon Musk has said a lot of stupid stuff about aging and longevity. From saying that people shouldn't live very long because society would ossify, to advocating that we judge people...

Once a year, Copenhagen becomes a Mecca for the longevity community. Hundreds of people flock to the picturesque Danish capital to attend the Aging Research and Drug Discovery Meeting (ARDD) for five full days of talks by geroscientists and biotech leaders, mingling and networking with like-minded longevity enthusiasts, and not-so-healthy late night-outs. ARDD is organized...

An article in GeroScience describes a previously unexplored relationship between FABP7, an inflammatory molecule that binds to fatty acids, and Alzheimer's disease. Not just a transporter Originally, as the authors explain, fatty acid binding proteins (FABPs) were considered to be simple biological chaperones that did not perform biological functions. Further research found that they play...