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February 26, 2021
One of the more interesting studies of cellular senescence in recent years was the demonstration that topical treatment with rapamycin, an inhibitor of mTOR signaling, over a period of months meaningfully reduced the burden of cellular senescence in the skin of aged individuals, leading to improvement in skin quality. It did not achieve this goal...
February 26, 2021
An interesting fact about the adaptive immune system: the number of T cells in the body remains much the same across the entire lifespan, even after the supply of new T cells all but ceases in middle age. T cells are created as thymocytes by hematopoietic cells in the bone marrow, and then mature in...
February 26, 2021
Changes in the gut microbiome have a role in aging, and the activities of microbial species (generation of beneficial metabolites, versus generation of harmful inflammation) may be as important as lifestyle choices such as exercise when it comes to the pace of aging. Certainly there is good evidence for rejuvenation of the gut microbiome via...
February 26, 2021
IMAGE: The fight between CD4 T-lymphocytes (in blue) against tumour cells (in orange). view more Credit: 2021 EPFL Hatice Altug Treatments for beating tumours are mainly based on CD8 T lymphocytes, which specialise in detecting and eliminating intracellular infections and in killing cancer cells. A large proportion of patients, however, do not respond to these treatments....
February 26, 2021
IMAGE: A comprehensive review of the recent cancer incidence, mortality, and risk factor data in China shows that it is possible to prevent the disease to a large extent, partly erasing... view more view more Credit: Cancer Biology & MedicineThe past century or so has seen unprecedented technological, scientific, and sociological evolution worldwide. These have accompanied global shifts...
February 26, 2021
IMAGE: Jeff Moran headshot view more Credit: Courtesy photo A Mason Engineering researcher has discovered that artificial microswimmers accumulate where their speed is minimized, an idea that could have implications for improving the efficacy of targeted cancer therapy. Jeff Moran, an assistant professor of mechanical engineering in the Volgenau School of Engineering, and colleagues from the...
