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Lifespan Research Institute

Creating a World Where Everyone Can Live Longer, Healthier Lives

Building A Global Ecosystem To Advance Research That Will Extend Healthy Human Lifespan

Lifespan.News

Bringing You The Latest News In the Field of Aging Research

We Are Building a Future Free of Age-Related Disease

Lifespan Research Institute is focused on strategically driving forward science to extend healthy human lifespan – through advocacy, ecosystem building, and direct support of cutting edge research into the root causes of aging.

Age-related diseases such as Alzheimer’s, heart disease, and cancer, cause untold harm – both in terms of personal suffering and socio-economic effects. Like treating the trunk of a tree as opposed to its various branches, it is a much more effective strategy to treat age-related maladies by addressing the process that is at the heart of them all, the aging process itself.

We conduct targeted scientific research with the explicit goal of accelerating the development of therapies that address the root causes of aging.

Learn More

Our educational programs offer several options for students interested in engaging with our mission of preventing age-related diseases.

Learn More

Through our investor network, we catalyze private investment in biotechnology companies developing interventions that target the root mechanisms of aging.

Learn More

We make the ground fertile for the entire field through advocacy initiatives that foster societal change, increasing available public and private funding for aging research.

Learn More

Addressing the Root Causes of Aging is a Much Better Way to Fight Disease

Healthy Life Expectancy and Total Life Expectancy Gained

Cure Cancer

2.5 Years

3 Years

Cure Heart Disease

4 Years

5 Years

Improved Aging

25+ Years

Research Highlights -

New Paper from LRI's Sharma Lab on Novel Senescent Cell Targeting

This study identifies an aberrant localization of the protein LAMP1 on the surface of senescent cells. Cells that presented LAMP1 on the surface showed clear signs of having a senescent/aged phenotype. The team was able to target LAMP1 on the surface of senescent cells to eliminate them.

LRI Needs Volunteers for Aging and Longevity Study.

Lifespan Research Institute is seeking volunteers for blood donations.

Your participation will help advance our understanding of the immune system and mitochondrial biology in aging.

Outreach Highlights -

Keith Comito Moderates Panel on the Geopolitics of Aging Research at the A4LI DC Summit

At the A4LI DC Summit Event, Keith Comito moderated the panel “Aging Populations: A Geopolitical Perspective” with Niklas Anzinger, Mac Davis, and Jasmine Smith, exploring how global demographic shifts toward aging populations impact societies, economies, and international cooperation.

Latest LRI News:

Gamma Delta T Cells Show Promise Against Cellular Senescence

Scientists from the Lifespan Research Institute have discovered that a subset of T cells effectively targets senescent cells and improves outcomes in a mouse model of idiopathic pulmonary fibrosis [1]. How do we harness the immune system against senescence? Cellular

Using a Surface Biomarker to Target Senescent Cells

Scientists have identified a senescence-associated surface protein that can be targeted using antibodies [1]. This discovery might help distinguish between beneficial and harmful senescent cells and could speed up the development of senolytic therapies. This work was done by the Lifespan

Nuclear Expression of a Mitochondrial Gene in Mice

Scientists from the Longevity Research Institute (LRI), which was formed by the merger of SENS Research Foundation and Lifespan.io, have achieved expression of an essential mitochondrial gene in the nucleus and proper functioning of the protein. This could pave the

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Creating a World Where Everyone Can Live Longer, Healthier Lives

Bringing You The Latest News In the Field of Aging Research

We Are Building a Future Free of Age-Related Disease

Lifespan Research Institute is focused on strategically driving forward science to extend healthy human lifespan – through advocacy, ecosystem building, and direct support of cutting edge research into the root causes of aging.

Our Research

We conduct targeted scientific research with the explicit goal of accelerating the development of therapies that address the root causes of aging.

Education Opportunities

Our educational programs offer several options for students interested in engaging with our mission of preventing age-related diseases.

Longevity Investor Network

Through our investor network, we catalyze private investment in biotechnology companies developing interventions that target the root mechanisms of aging.

Public Advocacy

We make the ground fertile for the entire field through advocacy initiatives that foster societal change, increasing available public and private funding for aging research.

Addressing the Root Causes of Aging is a Much Better Way to Fight Disease

Healthy Life Expectancy and Total Life Expectancy Gained

Cure Cancer

Cure Heart Disease

Improved Aging

Research Highlights -

New Paper from LRI's Sharma Lab on Novel Senescent Cell Targeting

This study identifies an aberrant localization of the protein LAMP1 on the surface of senescent cells. Cells that presented LAMP1 on the surface showed clear signs of having a senescent/aged phenotype. The team was able to target LAMP1 on the surface of senescent cells to eliminate them.

LRI Needs Volunteers for Aging and Longevity Study.

Lifespan Research Institute is seeking volunteers for blood donations.

Your participation will help advance our understanding of the immune system and mitochondrial biology in aging.

Outreach Highlights -

Keith Comito Moderates Panel on the Geopolitics of Aging Research at the A4LI DC Summit

At the A4LI DC Summit Event, Keith Comito moderated the panel “Aging Populations: A Geopolitical Perspective” with Niklas Anzinger, Mac Davis, and Jasmine Smith, exploring how global demographic shifts toward aging populations impact societies, economies, and international cooperation.

Latest LRI News:

Gamma Delta T Cells Show Promise Against Cellular Senescence

Using a Surface Biomarker to Target Senescent Cells

Nuclear Expression of a Mitochondrial Gene in Mice

About Us

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Receive our NewslEtter

We respect your privacy. You can unsubscribe at any time.

Creating a World Where Everyone Can Live Longer, Healthier Lives

Bringing You The Latest News In the Field of Aging Research

We Are Building a Future Free of Age-Related Disease

Lifespan Research Institute is focused on strategically driving forward science to extend healthy human lifespan – through advocacy, ecosystem building, and direct support of cutting edge research into the root causes of aging.

We conduct targeted scientific research with the explicit goal of accelerating the development of therapies that address the root causes of aging.

Our educational programs offer several options for students interested in engaging with our mission of preventing age-related diseases.

Through our investor network, we catalyze private investment in biotechnology companies developing interventions that target the root mechanisms of aging.

We make the ground fertile for the entire field through advocacy initiatives that foster societal change, increasing available public and private funding for aging research.

Addressing the Root Causes of Aging is a Much Better Way to Fight Disease​

Healthy Life Expectancy and Total Life Expectancy Gained

Cure Cancer

Cure Heart Disease

Improved Aging

Research Highlights -

This study identifies an aberrant localization of the protein LAMP1 on the surface of senescent cells. Cells that presented LAMP1 on the surface showed clear signs of having a senescent/aged phenotype. The team was able to target LAMP1 on the surface of senescent cells to eliminate them.

Lifespan Research Institute is seeking volunteers for blood donations.

Your participation will help advance our understanding of the immune system and mitochondrial biology in aging.

Outreach Highlights -

At the A4LI DC Summit Event, Keith Comito moderated the panel “Aging Populations: A Geopolitical Perspective” with Niklas Anzinger, Mac Davis, and Jasmine Smith, exploring how global demographic shifts toward aging populations impact societies, economies, and international cooperation.

Latest LRI News:

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We respect your privacy. You can unsubscribe at any time.

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Addressing the Root Causes of Aging is a Much Better Way to Fight Disease