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Fresh from Spain’s spectacular victory in the 2026 FIFA World Cup, Madrid is preparing for another kind of world-class gathering: one focused not on winning more years of sporting glory,
Researchers have discovered and explained how calcium mishandling in muscle cells leads to long-term muscle weakness in older people. Calcium is not just for bones Skeletal muscle cells use calcium
In a recent study, researchers have evaluated how responsive several DNA methylation (DNAm) biomarkers are to a range of longevity interventions [1]. Waiting too long Testing lifespan-extending interventions in humans
In a new study, semaglutide given late in life increased median lifespan in female mice by more than 12% and improved various health markers. Semaglutide’s effect possibly went beyond caloric
Researchers publishing in Aging Cell have described how stopping growth hormone receptor production in midlife significantly lengthens the lives of mice. Growth but diabetes Growth hormone affects the metabolism of
Filmmaker Tim Maupin has spent a number of years developing The Last Generation to Die, a near-future film about what happens when the first true rejuvenation technologies arrive and who
Driven by ongoing support from their community, The Longevity Science Foundation is extending the deadline for the Invested in Her campaign to October 1, 2026, as they work toward a
Properly untangling aging means untangling its various counterbalances, sometimes on the individual level. Here’s what’s been investigated this month. Interviews Wei-Wu He: People Should Become the CEOs of Their Own
Researchers have found that the sirtuin SIRT1 stabilizes the human genome by suppressing retrotransposition, which occurs when parts of the genome transcribe themselves onto other parts. When DNA modifies itself
Michael Snyder, Director of the Center for Genomics and Personalized Medicine at Stanford University, is obsessed with health-tracking wearables. During our interview, he wore four wrist-worn devices – watches and
A recent study has examined whether senescence might allow cancer cells to survive oncogene withdrawal and become even more dangerous [1]. Some blocking techniques are temporary Many cancers depend heavily
A new study compared high-intensity sprint-interval exercise with moderate-intensity exercise. The former produced larger changes in circulating protein and metabolite levels than the latter and stimulated proteins associated with cardiometabolic
Researchers have found that an upstream promoter of two extracellular matrix proteins increases healing and strength capabilities in the tendons of rats. Tendon injuries in older people Previous research has
A new study suggests that in amyotrophic lateral sclerosis – and possibly other neurodegenerative diseases – the brain’s immune cells devour stressed but still living neurons due to altered signaling
Using cohort studies and a mouse model, researchers have found that the circulating factor ANGPTL8, which is produced by senescent fat cells, is related to age-related diseases and mortality in