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Viva.city and BerlinHouse are opening Viva Frontier Tower, a 6-week popup village in the newly purchased 16-floor Frontier Tower in downtown San Francisco. From June 20 to August 4, this space will bring together people building the future in AI, Crypto, and Longevity. One Tower. Three Tracks. Endless Ideas. For 6 weeks, the tower will...

In a recent study that included data from humans, mice, and cell culture experiments, researchers demonstrated that gut microbes and their metabolites can profoundly influence the senescence of endothelial cells. They also explored the molecular processes underlying these changes [1]. Senescence in the blood vessels Endothelial cells line the inner surfaces of blood vessels, and...

Scientists have found that only about 1% of presented tumor antigens come from oncogenic mutations. The remaining 99%, previously overlooked, may offer better treatment targets [1]. Going after mutations Cancer arises from a series of mutations that drive abnormal cellular behaviors, such as runaway proliferation. Cancerous cells also normally present abnormal peptides on their surfaces...

In this interview, Boyang Wang of Immortal Dragons discusses the kinds of projects he wants to fund, ways in which the industry can be encouraged to develop, relationships between the East and West in longevity research and development, and what got him involved in longevity. Hello, and welcome to this Lifespan interview, where today, I...

Scientists have developed a new open source transcriptomic aging clock and published their work as a pre-print [1]. The newly identified rejuvenating drugs and gene perturbations could be applied in regenerative medicine and longevity therapies, and the aging perturbations could find use for anti-cancer therapies. Age-shift learning—one model for every platform Pasta (Predicting age-shift from...

While the overall prevalence of dementia might be rising due to population aging, a study has found that today’s older people seem to be less prone to dementia than in the past [1]. Are we having more dementia or less? While the robust rise in average life expectancy seen in the previous century has largely...