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Researchers have found that an upstream promoter of two extracellular matrix proteins increases healing and strength capabilities in the tendons of rats. Tendon injuries in older people Previous research
A new study suggests that in amyotrophic lateral sclerosis – and possibly other neurodegenerative diseases – the brain’s immune cells devour stressed but still living neurons due to altered
Using cohort studies and a mouse model, researchers have found that the circulating factor ANGPTL8, which is produced by senescent fat cells, is related to age-related diseases and mortality
This AI startup, which lists Nobel laureate David Baker among its co-founders, has announced a “world model” of a cell that can simulate both its natural state and responses
Researchers have gone into deep detail regarding how each of five senescent brain cell types expresses and receives factors that encourage other cells to become senescent. The contagion of
A massive human genetics study identified rare folliculin-interacting protein 1 (FNIP1) mutations associated with favorable metabolism and much lower cardiometabolic disease risk. Experiments in human liver cells and mice
In Aging, the Conboys and their team have described how a combination treatment kills both senescent and cancer cells and lengthens the lives of old mice. Of senescence and
Staying informed about health and longevity interventions can be tedious and time-consuming. Often it involves manually decoding a supplement label with numerous compounds, reading a blog post about some
A recent study identified the thymus hormone thymulin as a molecule with the potential to reduce inflammation in an age-dependent manner. Treating cancer-bearing mice with this molecule made other
A new study proposes a theoretical framework that explains why the more complex an animal is, the harder it is to move the needle on its rate of aging
Researchers have discovered why the protein AGGF1 has significant effects on blood pressure and published their findings in Aging Cell. Blood pressure is a condition of its own The
Human Longevity Inc., a company founded in 2013 by a trio of visionaries – Craig Venter, Peter Diamandis, and Robert Hariri – initially inspired high hopes. Several years and
A team of researchers has developed Pasta, a transcriptomic clock that accurately predicts the age-related effects of various compounds and gene expressions. Epigenetics versus transcriptomics The authors begin by
Worldwide healthcare faces an unsustainable situation. We spend trillions managing the late-stage effects of biological aging, yet routinely overlook the underlying causes that drive them. Driven by an aging
A new study has found that restricting dietary valine extends both median and maximum lifespan in male mice while improving healthspan in both sexes. The mechanism remains unclear, though