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We have spoken with Reason from Repair Biotechnologies about his company’s lead candidate, REP-0004, a drug targeting the liver to reduce excess intracellular free cholesterol. The FDA has granted
Most cardiovascular trials focus on lowering LDL cholesterol or reducing inflammation to slow disease progression. UDP-003 targets the root cause: toxic 7-ketocholesterol (7KC) inside macrophages and soft plaques. It
Cyclarity Therapeutics, Inc., a clinical stage biopharmaceutical company engineering cyclodextrin molecules into simple, scalable, and affordable therapies that bind and remove toxic targets to address root causes of age-related
This month, a group of researchers published an annual report on the clinical trials that are testing drugs for Alzheimer’s disease. Overall, they reported an increase in the number
We are super excited to share with you that today we released AI4L – “AI for Practical Longevity”, an open-source system that enables anyone to produce rigorous, evidence-based reviews
A new study suggests that GLP-1 receptor agonists do not affect muscle mass any more than weight loss caused by caloric restriction, and this appears to be true for
Dr. Junyue Cao is a professor at the Rockefeller University, and his lab develops ultra-high-throughput single-cell technologies and applies them to the biology of aging. In a recent paper
In Aging Cell, researchers have elucidated the relationship between intestinal aging and age-related changes to the gut microbiome. Two interdependent biologies The human gut works through the interaction of
In a new study, the popular supplement creatine seemed to add to some of the beneficial effects of power training [1]. Trying the combination in older people Exercise might
A new study has pit an advanced large language model against human physicians in tasks involving complex reasoning, treatment recommendations, and messy real-world patient records [1]. Testing a “thinking”
The Longevity Investor Network (LIN) was created to help bridge the gap between promising longevity startups and the investors capable of helping them scale. Through curated monthly pitch sessions,
Aging is a multifaceted topic, and it’s becoming more and more clear that the only way to deal with it is piece by piece. Here’s what pieces our industry
A perspective published in Aging Cell details the replacement-based approaches being investigated by several research organizations. Repair versus replacement This perspective begins by noting the inherent difficulty of rejuvenating
A recent study found an association between longer and more frequent daytime napping and higher mortality risk. The authors suggest using napping frequency and duration as behavioral markers of