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A new study has used aging trajectories of various cell types to predict diseases such as Alzheimer’s and lung cancer [1]. This
Researchers have found that sustained expression of excess hypoxia-inducible factor (HIF)-1α leads to unwanted formation of blood vessels (angiogenesis) that destroys cartilage
NeuroAge Therapeutics announced Younger 2027, a six-month biological aging contest in which competitors are measured on a clinical-grade aging panel and retested
A recent study suggests that hyperglycosylation in brain tissue can be a hallmark of Alzheimer’s disease [1]. Lesser-known Alzheimer’s molecular features Pathological
A new study links accelerated aging to early-onset solid cancers, while showing that this gap is becoming wider with each new generation
Researchers have found that bound pieces of RNA and DNA in the cytoplasm of senescent cells encourage these cells to secrete inflammatory
Scientists have targeted the thin fat layer around blood vessels with a transcription inhibitor, reducing symptoms of cardiometabolic disease [1]. When vessels
In Aging Cell, researchers have described the way that antioxidants work against senescence in muscle cells by altering mTOR signaling. Senescent cells
In a new study, muscle-targeted viral-vector-based delivery of the protein FGF21 significantly increased median lifespan in male mice and improved many healthspan
A team of reviewers has taken a look at the relationship between cancer, cellular senescence, and vascular overgrowth and published this information
Scientists have “faked” sleep in mice by artificially creating the on/off neuronal firing pattern similar to that seen in non-REM sleep. This
In a recent paper, researchers have proposed that the immune system and immune surveillance play a central role in maintaining microbial composition
In Aging Cell, researchers have described how a strain of Lactobacillus gut bacteria sends chemical signals that enter the bloodstream and decrease
As longevity moves from laboratory promise toward clinical validation, China is emerging as one of the largest demand bases shaping the field’s
Researchers have explained how a protein found in both yeast and humans facilitates the destruction of the core protein responsible for Parkinson’s