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All times are in Eastern Daylight Time (EDT).

Day 1, Thursday, August 20th

9:00 – 9:10 Welcome talk by LEAF President Keith Comito
9:10 – 9:20 Welcome talk by LEAF Vice President Oliver Medvedik, Director of the Maurice Kanbar Center for Biomedical Engineering
9:20 – 10:00 Opening keynote
Aubrey de Grey – SENS Research Foundation
Maximizing the pace of biomedical gerontology in a pandemic-conscious world
10:00 – 10:15 Q&A

10:15 – 11:45 Session 1: Biomarkers of aging

Steve Horvath – UCLA
Epigenetic Clocks for Clinical and Preclinical Applications
Polina Mamoshina – Insilico Medicine
Deep Biomarkers of Human Aging
Lorna Harries – University of Exeter
Alternative RNA processing: a new senotherapeutic target?
Premium Event
11:45 – 12:30 Panel Discussion: Biomarkers of aging: Significance for R&D and a path forward
11:45 – 12:15 Interview with Ron Kohanski (NIA)
12:15 – 12:30 Sponsor presentations

12:30 – 2:00 Session 2: Fundamental studies of the root mechanisms of aging, part 1

Alexey Moskalev – Institute of Biology of the Komi Science Centre of the Ural Division of RAS
Genetic mechanisms of aging and longevity on the Drosophila model
Judith Campisi – The Buck Institute for Research on Aging
Targeting senescent cells to alleviate aging: A simple task?
Irina Conboy – UC Berkeley
Preventing, attenuating and reversing diseases of old age as a class: young blood is not required
Premium Event
2:00 – 2:45 Panel discussion: Public perception of research on aging
2:00 – 2:30 Poster Session
Three 10-minute presentations by young researchers
2:30 – 2:45 Interview with Daria Khaltourina (International Longevity Alliance)

2:45 – 4:15 Session 3: Fundamental studies of the root mechanisms of aging, part 2

Andrei Gudkov – Roswell Park
Comprehensive Cancer Center Topic TBA
Vadim Gladyshev – Harvard Medical School
Quantifying and manipulating the aging process
Additional speakers TBA
4:15 – 4:45 Interview with David Wood (London Futurists)
4:45 – 5:00 Interview TBA
5:00 – 5:45 Panel Discussion: Aging and COVID-19: finding synergy in research and advocacy
5:45 – 6:00 PM Notes by the Chair

Day 2, Friday, August 21st

9:00 – 9:05 Welcome talk by LEAF VP Oliver Medvedik
9:05 – 9:45 Opening keynote
Brian Kennedy – National University of Singapore
Preventive Medicine in an Ageing Society (Beyond Healthcare to Health)
9:45 – 10:00 Q&A

10:00 – 11:00 Session 4: Investing in rejuvenation, part 1

David Gobel – Methuselah Foundation
Rejuvenation In The Time of Pandemic
Alexandra Bause – Apollo Ventures
Biotech VC meets Impact Investing with the Mission to Enhance Human Health
Premium Event
11:00 – 11:45 LEAF Panel Discussion: Role of media in engaging early adopters
11:00 – 11:30 Interview with Michael Greve (Forever Healthy Foundation)
11:30 – 11:45 Sponsor presentations

11:45 – 12:45 Session 5: Investing in rejuvenation, part 2

Sergey Young – Longevity Vision Fund
5 Investment Lessons from Coronavirus
Javier Noris – Lifespan.io
The Longevity Impact Fund – Funding Translational Longevity Research
12:45 – 1:30 Panel Discussion: How to Overcome the Valley of Death?

1:30 – 3:00 Session 6: Targeting aging with interventions, part 1

Lewis Gruber – SIWA Therapeutics
A Comprehensive Therapy for Cancer and Other Aging-Associated and Degenerative Diseases – Attacking Senescent Cells and Cancer Cells Simultaneously
James Kirkland – Mayo Clinic
Topic TBA
Marco Quarta – Rubedo Life Sciences
Topic TBA
3:00 – 3:15 Interview with Mair Underwood (University of Queensland)

3:15 – 4:45 Session 7: Targeting aging with interventions, part 2

Reason – Repair Biotechnologies
Towards Reversal of Atherosclerosis
Hanadie Yousef – Juvena Therapeutics
Harnessing the Regenerative Secretome of Pluripotent Stem Cells to Rejuvenate Aged Tissues
Matthew Oki O’Connor – SENS Research Foundation, Underdog
Engineering drugs for the removal of toxic metabolites with aging
4:45 – 5:00 Interview TBA

5:00 – 5:55 Session 8: Targeting aging with interventions, part 3

Peter Fedichev – GERO
Engineering rejuvenation therapeutics with AI
Joshua Mittledorf – School of Medicine, Washington University in St Louis
Are Methylation Clocks a Reliable Gauge of Anti-Aging Interventions?
5:55 – 6:00 PM Closing remarks by LEAF President Keith Comito

Lifespan Factory – On-Demand Track

Kelsey Moody – Ichor Therapeutics
2019 Workshop “Developing a Biotechnology Startup in the Rejuvenation Field”
Isabelle Schiffer – Forever Healthy Foundation
Rejuvenation therapies from bench to bedside – where are we now?
Thomas Weldon – Ponce de Leon Health
How to reverse your epigenetic age now
Anar Isman – AgelessRx
TBA
Ronjon Nag – R42 Group
TBA
Tyler Golato – Molecule
TBA