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All times are in Eastern Daylight Time (EDT).
Day 1, Thursday, August 20th
| 9:00 – 9:10 Welcome talk by LEAF President Keith Comito |
| 9:10 – 9:20 Welcome talk by LEAF Vice President Oliver Medvedik, Director of the Maurice Kanbar Center for Biomedical Engineering |
| 9:20 – 10:00 Opening keynote Aubrey de Grey – SENS Research Foundation Maximizing the pace of biomedical gerontology in a pandemic-conscious world 10:00 – 10:15 Q&A |
10:15 – 11:45 Session 1: Biomarkers of aging |
| Steve Horvath – UCLA Epigenetic Clocks for Clinical and Preclinical Applications |
| Polina Mamoshina – Insilico Medicine Deep Biomarkers of Human Aging |
| Lorna Harries – University of Exeter Alternative RNA processing: a new senotherapeutic target? |
| Premium Event 11:45 – 12:30 Panel Discussion: Biomarkers of aging: Significance for R&D and a path forward |
| 11:45 – 12:15 Interview with Ron Kohanski (NIA) |
| 12:15 – 12:30 Sponsor presentations |
12:30 – 2:00 Session 2: Fundamental studies of the root mechanisms of aging, part 1 |
| Alexey Moskalev – Institute of Biology of the Komi Science Centre of the Ural Division of RAS Genetic mechanisms of aging and longevity on the Drosophila model |
| Judith Campisi – The Buck Institute for Research on Aging Targeting senescent cells to alleviate aging: A simple task? |
| Irina Conboy – UC Berkeley Preventing, attenuating and reversing diseases of old age as a class: young blood is not required |
| Premium Event 2:00 – 2:45 Panel discussion: Public perception of research on aging |
| 2:00 – 2:30 Poster Session |
| Three 10-minute presentations by young researchers |
| 2:30 – 2:45 Interview with Daria Khaltourina (International Longevity Alliance) |
2:45 – 4:15 Session 3: Fundamental studies of the root mechanisms of aging, part 2 |
| Andrei Gudkov – Roswell Park Comprehensive Cancer Center Topic TBA |
| Vadim Gladyshev – Harvard Medical School Quantifying and manipulating the aging process |
| Additional speakers TBA |
| 4:15 – 4:45 Interview with David Wood (London Futurists) |
| 4:45 – 5:00 Interview TBA |
| 5:00 – 5:45 Panel Discussion: Aging and COVID-19: finding synergy in research and advocacy |
| 5:45 – 6:00 PM Notes by the Chair |
Day 2, Friday, August 21st
| 9:00 – 9:05 Welcome talk by LEAF VP Oliver Medvedik |
| 9:05 – 9:45 Opening keynote Brian Kennedy – National University of Singapore Preventive Medicine in an Ageing Society (Beyond Healthcare to Health) 9:45 – 10:00 Q&A |
10:00 – 11:00 Session 4: Investing in rejuvenation, part 1 |
| David Gobel – Methuselah Foundation Rejuvenation In The Time of Pandemic |
| Alexandra Bause – Apollo Ventures Biotech VC meets Impact Investing with the Mission to Enhance Human Health |
| Premium Event 11:00 – 11:45 LEAF Panel Discussion: Role of media in engaging early adopters |
| 11:00 – 11:30 Interview with Michael Greve (Forever Healthy Foundation) |
| 11:30 – 11:45 Sponsor presentations |
11:45 – 12:45 Session 5: Investing in rejuvenation, part 2 |
| Sergey Young – Longevity Vision Fund 5 Investment Lessons from Coronavirus |
| Javier Noris – Lifespan.io The Longevity Impact Fund – Funding Translational Longevity Research |
| 12:45 – 1:30 Panel Discussion: How to Overcome the Valley of Death? |
1:30 – 3:00 Session 6: Targeting aging with interventions, part 1 |
| Lewis Gruber – SIWA Therapeutics A Comprehensive Therapy for Cancer and Other Aging-Associated and Degenerative Diseases – Attacking Senescent Cells and Cancer Cells Simultaneously |
| James Kirkland – Mayo Clinic Topic TBA |
| Marco Quarta – Rubedo Life Sciences Topic TBA |
| 3:00 – 3:15 Interview with Mair Underwood (University of Queensland) |
3:15 – 4:45 Session 7: Targeting aging with interventions, part 2 |
| Reason – Repair Biotechnologies Towards Reversal of Atherosclerosis |
| Hanadie Yousef – Juvena Therapeutics Harnessing the Regenerative Secretome of Pluripotent Stem Cells to Rejuvenate Aged Tissues |
| Matthew Oki O’Connor – SENS Research Foundation, Underdog Engineering drugs for the removal of toxic metabolites with aging |
| 4:45 – 5:00 Interview TBA |
5:00 – 5:55 Session 8: Targeting aging with interventions, part 3 |
| Peter Fedichev – GERO Engineering rejuvenation therapeutics with AI |
| Joshua Mittledorf – School of Medicine, Washington University in St Louis Are Methylation Clocks a Reliable Gauge of Anti-Aging Interventions? |
| 5:55 – 6:00 PM Closing remarks by LEAF President Keith Comito |
Lifespan Factory – On-Demand Track
| Kelsey Moody – Ichor Therapeutics 2019 Workshop “Developing a Biotechnology Startup in the Rejuvenation Field” |
| Isabelle Schiffer – Forever Healthy Foundation Rejuvenation therapies from bench to bedside – where are we now? |
| Thomas Weldon – Ponce de Leon Health How to reverse your epigenetic age now |
| Anar Isman – AgelessRx TBA |
| Ronjon Nag – R42 Group TBA |
| Tyler Golato – Molecule TBA |
