You can download a copy of the event abstracts booklet here should you wish to do so.
Day 1, Thursday, July 11th
| 8:00 – 9:00 Registration, Networking |
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9:00 – 9:10 Welcome talk by LEAF President Keith Comito 9:10 – 9:15 Welcome from Maurice Kanbar Center for Biomedical Engineering Director Oliver Medvedik |
9:15 – 9:45 Opening Keynote |
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Aubrey de Grey – SENS Research Foundation Estimating the true complexity of comprehensive rejuvenation |
09:45 – 11:30 Session 1 – Biomarkers of aging |
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Morgan Levine – Yale Center for Research on Aging (Y-Age) DNA methylation landscapes in aging and age-related diseases Qingsong Zhu – Insilico Medicine Deep Learned biomarkers for aging research Doug Ethell – Leucadia Therapeutics Predicting Alzheimer’s disease with deep learning Michael Lustgarten – Tufts University Role of the gut microbiome on muscle strength in older adults; My n=1 data and the quest for optimal health and lifespan |
| 11:30 – 11:40 Sponsor presentations |
| 11:40 – Noon Coffee break |
Noon – 1:45 Session 2 – Fundamental studies on the root mechanisms of aging, Part 1 |
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George Church – Harvard Medical School Aging-related gene, cell, & organ therapies Judith Campisi – The Buck Institute for Research on Aging Puzzles and promises of cellular senescence Andrei Gudkov – Roswell Park Comprehensive Cancer Center ‘Retrobiome’ in aging: Intrinsic mechanisms of systemic DNA damage by retroelements and therapeutic approaches to prevent it Vera Gorbunova – University of Rochester From long-lived species to anti-aging interventions |
| 1:45 – 2:30 Lunch |
2:30 – 3:20 Session 3 – Fundamental studies on the root mechanisms of aging, Part 2 |
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Vadim Gladyshev – Harvard Medical School From longevity signatures to longevity interventions Amutha Boominathan – SENS Research Foundation Remediation of mitochondrial DNA defects via allotopic expression |
| 3:20 – 4:00 Panel discussion: Unlocking funding for basic research on the mechanisms of aging |
| 4:00 – 4:30 Coffee break |
4:30 – 6:40 Session 4 – Encouraging progress in aging research |
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Michael Greve – Forever Healthy Foundation Accelerating the availability of rejuvenation therapies João Pedro de Magalhães – University of Liverpool Prospects, problems and pitfalls in developing aging therapeutics Huda Suliman – Icaria Life Sciences Icaria Life Sciences, Inc. – Your partner for aging research Justin Rebo – BioAge Building a pipeline of therapies that treat aging |
| 6:40 – 7:00 Networking |
Day 2, Friday, July 12th
| 8:00 – 9:00 Registration, Networking |
| 9:00 – 9:10 Welcome talk by Maurice Kanbar Center for Biomedical Engineering Director Oliver Medvedik |
9:10 – 9:40 Opening Keynote |
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Ronald Kohanski – NIA Concepts and perspectives in geroscience |
9:40 – 11:30 Session 5 – Creating interventions against aging, Part 1 |
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María Blasco – CNIO Telomere-based therapeutic strategies for cancer and age-related diseases Michael West – AgeX Therapeutics The reversal of the aging of human cells: strategies for clinical implementation Greg Fahy – Intervene Immune Intervene Immune: Reversing human aging right now! Reason – Repair Biotechnologies Developing therapies for thymus regeneration and atherosclerosis reversal |
| 11:30 – 11:40 Sponsor presentations |
| 11:40 – Noon Coffee break |
Noon – 1:45 Session 6 – Creating interventions against aging, Part 2 |
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Kelsey Moody – Ichor Therapeutics Towards enzyme augmentation therapy (EAT) for macular degeneration Pam Maher – Salk Institute for Biological Studies Novel anti-aging compounds based on natural products for the treatment of Alzheimer’s disease John Lewis – Oisin Biotechnologies Systemic senolysis in naturally aged mice Jared Fischer – Oregon Health and Science University Rationally designed FOXO4-p53 interfering peptide selectively kills chemotherapy-induced senescent and dormant cancer cells in vivo |
| 1:45 – 2:30 Lunch |
2:30 – 3:50 Session 7 – Creating interventions against aging, Part 3 |
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Kevin Strange – Novo Biosciences Rethinking regenerative medicine: developing small molecule drugs that unlock our innate regenerative potential Jay Sarkar – Turn.bio Epigenetic reprogramming for multifaceted reversal of aging phenotypes Peter Fedichev – GERO Hacking aging: a data-driven approach to healthy life extension |
| 3:50 – 4:30 Panel discussion: Unlocking a future without age-related diseases: a forecast |
| 4:30 – 5:00 Coffee break |
5:00 – 6:15 Session 8 – Investors’ perspectives on developing a rejuvenation industry |
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Joe Betts-Lacroix – YCombinator The law of the instrument James Peyer – Kronos BioVentures Addressing the most challenging problems in longevity with a VentureLabs model Sree Kant – Life Biosciences Novel investment paradigms in aging research |
| 6:15 – 6:55 Panel discussion: Dialogue between investors and rejuvenation biotech |
| 6:55 – 7:00 Closing remarks by LEAF President Keith Comito |
| 7:00 – 7:30 Networking |