Apple Cider Vinegar: Benefits, Myths, and Side Effects

Apple cider vinegar
Apple Cider Vinegar: Benefits, Myths, and Side Effects
Date Published: 05/04/2023
Date Modified: 09/14/2023
Apple cider vinegar

Apple cider vinegar has been touted as a useful and effective natural remedy for centuries, with claims of its ability to cure or treat numerous ailments and health conditions. The first known people to use apple cider vinegar as a remedy were the ancient Babylonians, dating back to around 5,000 BCE. They used it for medicinal purposes as well as for food preservation and flavoring. The ancient Greeks and Romans also incorporated apple cider vinegar into their medical practices. As with many traditional remedies, the actual scientific evidence for these claims varies, with some being supported by research and others lacking scientific bases [1].

Active constituents in apple cider vinegar

Apple cider vinegar contains several components that may contribute to its purported medicinal effects:

  1. Acetic acid: The primary active component in any vinegar, acetic acid is produced during the fermentation process. It is responsible for the sour taste and pungent smell of vinegar. Acetic acid has antimicrobial properties and may help control blood sugar levels [2, 3].
  2. Malic acid: This organic acid found in apple cider vinegar and contributes to its sour taste. Malic acid has been associated with potential benefits, such as improved digestion and reduced muscle pain [4].
  3. Tartaric acid: This organic acid is also found in apple cider, and some studies have linked it to lower blood pressure [5].
  4. Polyphenols: Apple cider vinegar contains various polyphenols, such as chlorogenic acid, which are plant-based compounds with antioxidant properties. These antioxidants are reported to help protect cells against oxidative stress and may reduce the risk of chronic diseases [6, 7].
  5. Enzymes: The raw, unfiltered version of apple cider vinegar contains enzymes that are suggested to support digestion and promote a healthy gut, including amylase, protease, lipase, pectinase, and cellulase [7].

Separating Myths from Scientific Facts

No single food or supplement can cure or prevent all illnesses, and apple cider vinegar is not a panacea. There is little scientific evidence to support the claim that apple cider vinegar can dissolve or prevent kidney stones. Kidney stones are often composed of calcium oxalate, which does not dissolve in acetic acid. While apple cider vinegar has been anecdotally used for kidney stone relief, it is essential to consult a healthcare professional for proper diagnosis and treatment [8].

The idea that apple cider vinegar can help “detoxify” the body is largely a myth. The human body has natural mechanisms for removing toxins, primarily through the liver and kidneys. There is little scientific evidence to suggest that consuming apple cider vinegar can enhance or replace these processes. Maintaining a healthy lifestyle, including a balanced diet, regular exercise, and proper hydration, is a more effective approach.

Β This is not to say there is no evidence; for example, a 2022 study found that mulberry vinegar attenuates the effects of inflammatory responses induced by lipopolysaccharide, a very potent endotoxin, on C6 glial cells. It is not clear whether acetic acid, a defining constituent of all vinegars, or the potent antioxidant anthocyanins found in mulberries were responsible for this effect [9]. Furthermore, this was an experiment in a dish with cells, which is very different from a clinical trial. Such experiments seldom translate to effective use in humans.

Blood sugar, weight loss, and antimicrobial properties

One of the most scientifically supported benefits of apple cider vinegar is its ability to help regulate blood sugar levels. Multiple studies have demonstrated that it can improve insulin sensitivity and reduce blood sugar spikes, particularly when consumed before or with a high-carbohydrate meal. This effect may be particularly beneficial for people with type 2 diabetes or those at risk for developing the condition [3, 10-13].

Apple cider vinegar has been linked to modest weight loss in some studies. It has been reported to increase feelings of fullness, thereby reducing overall calorie intake. However, it is not a magic weight loss solution. Combining apple cider vinegar with a balanced diet and regular exercise is the most effective approach to achieve and maintain a healthy weight [14-17].

Apple cider vinegar has been found to possess antimicrobial properties due to its acetic acid content. This has led to its use as a natural preservative and in the treatment of minor skin infections or irritations. However, it should be used with caution on the skin, as it can cause irritation or burns if not appropriately diluted [2, 18-22].

Cardiovascular health and cancer

While some studies have suggested that apple cider vinegar may have a positive impact on cardiovascular health, such as reducing blood pressure and improving cholesterol levels, the evidence is limited and inconsistent. More research is needed to determine the extent of these potential benefits and the optimal dosage and duration of its consumption.

A study conducted on rats found that acetic acid, a primary component of apple cider vinegar, may help reduce blood pressure by inhibiting the enzyme responsible for constricting blood vessels [23, 24]. In a more recent study, Tartaric acid, another acid present in apple cider vinegar, has also been shown to lower blood pressure [5]. However, more research, particularly in humans, is needed to confirm these findings and determine if there is an optimal consumption for blood pressure management [25].

Some animal studies have shown that apple cider vinegar may improve cholesterol levels by reducing low-density lipoprotein (LDL) “bad” cholesterol and increasing high-density lipoprotein (HDL) “good” cholesterol. However, the evidence in humans is limited, and more research is needed to confirm these effects and establish appropriate dosages and guidelines for use in managing cholesterol levels [6, 7, 26].

Apple cider vinegar contains polyphenols, including chlorogenic acid, which are known to have antioxidant properties. Antioxidants can help protect cells from damage caused by free radicals, which are believed to contribute to the development of cardiovascular disease. However, the direct impact of apple cider vinegar’s antioxidant properties on cardiovascular health remains unclear and requires further investigation.

In vitro studies have demonstrated that acetic acid, the primary component of apple cider vinegar, may slow the growth of some cancer cells. However, these studies were conducted on isolated cells in a laboratory setting, so the results cannot be directly applied to humans [7, 27].

In summary, apple cider vinegar has been shown to improve control over blood sugar, promote modest weight loss, and possess antimicrobial properties. However, many other claims about the efficacy of apple cider vinegar in treating various ailments have not been scientifically validated. This does not mean all of those claims are invalid. Scientific validation of medicinal claims requires a significant expenditure of money, which is often not available for unpatentable or natural products.

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About the author

Stephen Rose

Chris is one of the writers at Lifespan.io. His interest in regenerative medicine and aging emerged as his personal training client base grew older and their training priorities shifted. He started his masters work in Bioengineering at Harvard University in 2013 and is currently completing his PhD at SUNY Polytechnic University in Albany, NY. His dissertation is focused on the role of the senescent cell burden in the development of fibrotic disease. His many interests include working out, molecular gastronomy, architectural design, and herbology.