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April 17, 2024
A recent paper published in Nature Aging dives into the gene expression differences between young, middle-aged, and older human ovaries and tests possible interventions to slow down their aging processes [1]. An underexplored area of human aging Female reproductive aging remains a relatively unexplored area of study. With people living longer and females postponing childbearing,...
April 10, 2024
The authors of a recent study published in Aging Cell tested 21 groups of medication used by the elderly and reported that some of them impact aging biomarkers [1]. Repurposing existing drugs to fight aging The search for drugs that slow aging includes finding new compounds and repurposing already-known drugs. Animal studies have suggested that...
April 03, 2024
Recent research has contributed to the growing body of evidence regarding social isolation, loneliness, and biological aging [1]. Social isolation is not generally screened for During doctor visits, patients are often screened for many physical conditions. However, screening for social isolation in the clinic is not as common as it should be, despite the evidence...
March 27, 2024
Scientific Reports has published a study that used a computational approach to identify natural senotherapeutics that have a similar impact on gene expression as a known senotherapeutic drug, dasatinib [1]. Drug combinations for better treatments Cellular senescence, a state in which cells cannot divide anymore but are still metabolically active and often display senescence-associated secretory...
March 20, 2024
In a recent Nature Communications paper, the researchers investigated changes in weight, metabolism, and microbiome that resulted from periodic restricted feeding in non-human primates [1]. Continuous vs. time-restricted caloric restriction Caloric restriction, which limits the amount of calories an organism consumes, is a widely known lifespan-extending intervention in laboratory animals [2]. How caloric restriction is...
March 13, 2024
The authors of a paper published in Pharmaceuticals tested multiple drug-polyphenol combinations to find the ones with the best senolytic properties [1]. Targeting senescent cells in lung diseases Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are...