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Tag: Telomere Attrition

Telomeres on chromosomes
Scientists have identified a small molecule that upregulates telomerase reverse transcriptase (TERT) in multiple tissues, improving health and cognition in old mice. Telomere attrition and health Why We Age: Telomere AttritionTelomeres are DNA regions located at the ends of a chromosome. Their normal length is 8-10 thousand base pairs, yet they consist of repetitions of...
Chromosomes
A recent study from Penn State University may shed more light on the link between telomeres, aging, and why caloric restriction appears to influence them. Telomeres are linked to aging Telomeres are small protective caps on the ends of our chromosomes that guard our DNA. Telomere attrition, in which these caps slowly erode, is a...
Stress in pregnancy
A new study published in BMC Psychiatry reviewed literature that links perceived stress during pregnancy with newborns' telomere length [1]. Lifelong impact of telomere length Telomeres are protective caps at the end of chromosomes. The shortening of the telomeres, which happens with each DNA replication cycle [2], is one of the Hallmarks of Aging. Why...
An image of telomeres shortening which could lead to DNA damage.
Since its launch in 2016, Rejuvenation Technologies, located in Mountain View, California, has been developing a therapeutic to restore telomeres in humans. The company has been in stealth mode for a number of years, but there is finally some news! Reversing a decade of telomere loss in one treatment Rejuvenation Technologies has created a method...
Elderly muscle
Researchers publishing in Cell Proliferation have described factors that appear to give old muscle stem cells the ability to effectively proliferate and differentiate for a very long time. When renewal runs out Why we Age: Stem Cell ExhaustionStem cell exhaustion is the age-related deficiency of stem cells. This particular hallmark is directly responsible for many...
Exercising people
Researchers publishing in BMC Medicine have found that there is a relationship between biomarkers of aging and measurements of health and mental well-being [1]. "Healthy lifestyle" is not just a phrase It is very well known that unhealthy behaviors are strongly linked to adverse health outcomes. For example, alcoholism is a significant risk factor for...