Tag: OSK

Dr. Belmonte’s group at Altos Labs targeted stressed and senescent cells with partial reprogramming, producing large increases in lifespan in male mice [1]. What are they doing there? Since the discovery of cellular reprogramming almost two decades ago, a lot of hopes have been put into this technology, and a lot of progress has been...

In Nature Communications, Ali Yücel and Vadim Gladyshev have published a review of the current state of the art in partial cellular reprogramming, detailing what this technology does and how it might be used safely. Affecting methylation directly Yamanaka Factors - Opportunities for RejuvenationDrs. Takahashi and Yamanaka showed that they could use Oct4, Sox2, Klf4, and...

In a new study, scientists have achieved significant improvement of glaucoma in a mouse model via partial cellular reprogramming of retinal cells. However, it might take more than that to reverse other aspects of age-related vision loss [1]. The vision of restored vision The group that authored this paper, led by the prominent geroscientist Dr....