Tag: Obesity

Scientists have found that visceral fat and subcutaneous fat produce different responses to obesity in male mice and human patients and identified an important regulator of these processes [1]. The tale of the two fats It has been known that visceral fat, which accumulates around organs in the abdomen, and subcutaneous fat, which accumulates under...

Some longevity biotech companies fit neatly into one of the big buckets we have in this field, like senolytics or cellular reprogramming. Others, such as Junevity, a small spin-out from the University of California, San Francisco, dare to walk an unbeaten path. Junevity pursues the ambitious goal of fixing age-related transcriptional dysregulation using short interfering...

New research demonstrated how transitioning from a typical Western diet composed of processed foods to a whole-food diet improved cardiometabolic health and body composition and impacted gut microbiome metabolites in elderly people [1]. You are what you eat While this study was conducted in Australia, the foods commonly consumed there are similar to common foods...

A team of researchers has waded into a controversial and contradictory area of study, publishing information on the link between obesity and an inflammatory molecule that increases with aging. A context-dependent molecule The authors point out previous research that singled out the interleukin IL-6, a key immune signaling molecule, as a major contributor to inflammaging...

A new study suggests that the reason why aging is associated with obesity lies in specific neurons found in the brain [1]. Tell that to the brain It is often hard to lose weight, and it becomes harder with age. While it seems simple enough to eat less, signals in the brain are telling people to...

According to a paper published in Aging, a fisetin derivative that is being investigated for brain protection may also be effective in controlling glucose and ameliorating obesity. Repurposing a repurposed compound CMS121, the focus of this study, was created by modifying fisetin, a flavonol that is well known for its effects against cellular senescence. CMS121...